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Associate Biologist – Automated Protein Expression

Job in San Diego, San Diego County, California, 92121, USA
Listing for: Eli Lilly
Full Time position
Listed on 2026-08-30
Job specializations:
  • Research/Development
    Research Scientist, Biotech Research, Drug Discovery
Job Description & How to Apply Below

Join Lilly:
Associate Scientist in Biologics Automation and High-throughput Technologies

At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve.

This is hard, urgent, selfless work—but it's work worth doing. If you're driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us.

The Biologics Automation and High-throughput Technologies Group at the Lilly Biotechnology Center in San Diego is seeking a versatile Associate Scientist to accelerate early drug discovery through innovative protein expression and purification technologies. Join our dynamic team where you'll leverage state-of-the-art automated systems to drive breakthrough therapeutics from concept to reality.

In this role, you will be at the forefront of high-throughput biologics production, directly impacting the speed and success of our drug discovery pipeline.

Key Objectives/Deliverables:
  • Mammalian cell line maintenance, including culture expansion, harvesting, and cryopreservation
  • Master complex integrated liquid handling platforms to execute high-throughput transfections and plate-based purifications (protein A/G/HIS capture)
  • Ensure scientific rigor through reagent preparation and validation, meticulous process documentation, QC execution, and expression performance monitoring
  • Serve as a technical liaison between automation teams, requestors, and collaborators to optimize biological outcomes and resolve process challenges
  • Drive improvement by identifying workflow bottlenecks, implementing innovative solutions, and expanding platform capabilities through independent initiative and collaborative partnerships
  • Partner with antibody discovery, protein engineering, and purification teams across sites to share insights, accelerate learning, and anticipate evolving business needs
Basic Qualifications:
  • Bachelor's Degree in biological sciences (biology, molecular biology, biochemistry or similar disciplines)
  • Experience in tissue culture (aseptic technique) required
Additional Skills/Preferences :

Technical Excellence:

  • Understanding of protein expression and purification techniques preferred
  • Hands-on experience with automation equipment (e.g., Bio Mek liquid handlers, reagent dispensers) advantageous
  • Experience with integrated liquid handling platforms and/or laboratory automation scheduling software not required but beneficial
  • Demonstrated proficiency in Microsoft Office applications (Excel, Word, PowerPoint)
  • Programming skills, experience leveraging AI tools to enhance productivity and scientific workflows, and robust statistical background highly valued
  • Strong data analysis capabilities with meticulous attention to detail
Professional Attributes:
  • Outstanding written and verbal communication skills with ability to translate complex technical concepts
  • Proven ability to excel both independently and within collaborative team environments
  • Demonstrated learning agility and adaptability in fast-paced settings
  • Strong organizational and work planning capabilities
Why This Role Matters:

This position offers a unique opportunity to work at the intersection of biology and automation, where your contributions will directly accelerate the discovery of life-changing medicines. You'll have access to industry-leading technology, collaborate with world-class scientists, and develop expertise that will define the future of automated drug discovery.

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form for further assistance. Please note this is for individuals to request an accommodation as part of the application…

Position Requirements
10+ Years work experience
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