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Director, Medicinal Chemistry—Lead Molecule Discovery

Job in San Diego, San Diego County, California, 92189, USA
Listing for: Vertex Pharmaceuticals LLC
Full Time position
Listed on 2026-08-31
Job specializations:
  • Research/Development
    Drug Discovery, Pharmaceutical Science/ Research
  • Pharmaceutical
    Drug Discovery, Pharmaceutical Science/ Research
Salary/Wage Range or Industry Benchmark: 198000 - 296000 USD Yearly USD 198000.00 296000.00 YEAR
Job Description & How to Apply Below
Position: Director, Medicinal Chemistry—Lead Small Molecule Discovery

Vertex is seeking a Director of Medicinal Chemistry to provide people management and strategic leadership for small-molecule discovery programs, guiding design and optimization from early discovery through candidate selection. This on-site role requires deep scientific expertise and a proven track record of advancing discovery programs in a fast-paced research environment.

You will mentor a chemistry team, partner with biology, DMPK, toxicology, and pharmaceutical sciences, and help shape

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