Senior Research Associate, Discovery Biology

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Full Time Scientist San Diego, CA, San Diego, CA, US

30+ days ago Requisition

Salary Range: $75,000.00 To $85,000.00 Annually

We are seeking a motivated and organized Senior Research Associate who aspires to make a meaningful impact on patients’ lives across multiple therapeutic areas. This is an exciting opportunity to join our Discovery Biology team and contribute to the discovery and development of next-generation oligonucleotide therapeutics within a fast‑paced, collaborative, and innovative research environment.

The successful candidate will play a key role in the design and execution of in vivo studies and downstream analyses, including qPCR, ELISA, Western blotting, and other molecular and cellular assays. In addition, this individual will help manage and maintain animal colonies while gaining exposure to a broad range of drug discovery activities. We are looking for a scientifically curious, hands‑on team player who is eager to learn new techniques, expand their skill set, and grow alongside a dynamic research organization.

• Develop and promote a workplace culture that values diversity of thought, promotes integrity and creates an atmosphere that supports coaching and fosters accountability.
• Carry out assigned laboratory functions applying knowledge and skill in an accurate, timely manner.
• Establish and maintain excellent working relationships with critical collaborative partners throughout the company.
• Contribute to the advancement of preclinical discovery programs across multiple therapeutic areas by supporting the design, execution, analysis, and troubleshooting of in vivo studies and associated downstream assays.
• Independently plan and prioritize activities to ensure the timely completion of assigned objectives and project deliverables.
• Manage and maintain mouse colonies, including coordinating study logistics, animal ordering, breeding strategies, and experimental scheduling to support in vivo research programs.
• Track progress against project timelines, generate regular status updates, and communicate progress and issues to management.
• Maintain accurate experiment records in various internal databases and perform basic data analysis.
• Continuously expand technical expertise by learning and implementing new experimental techniques and contributing to the development of innovative research approaches.
• Train and mentor entry‑level staff.
• Manage and maintain equipment, consumables and dedicated laboratory environment needed to carry out assignments;
  Troubleshoot and solve equipment/technical problems.
• Maintain updated and well‑organized lab notebooks.
• Execute daily laboratory operations with an approach designed to minimize risks and hazard waste streams.
• Maintain all appropriate corporate standards for facility safety and hazardous material management.
• Other duties as assigned.

Essential Physical Characteristics:

Reasonable accommodation(s) may be made to enable qualified individuals with disabilities to perform the essential functions of a job, on a case‑by‑case basis.

On‑Site Protocol:

Physical presence at the ADARx Pharmaceuticals worksite is a necessary job function of this role, which the Company deems critical to collaboration, innovation, productivity, employee well‑being and engagement, and it enhances the Company culture.

Qualifications:

• BA/BS in Biological sciences and have minimum of 8 years of experience in research, 3 years in industry, or MA/MS plus minimum of 5 years of experience in research, including 3 years in industry.
• Hands‑on experience designing, executing, troubleshooting, and interpreting in vivo studies that support drug discovery and therapeutic development programs.
• Solid understanding of IACUC regulations, animal welfare standards, and best practices for conducting in vivo research.
• Experience managing and maintaining mouse colonies, including animal tracking, breeding coordination, and study management.
• Experience collecting blood and tissue samples from rodents and processing…