Scientist IV, Pharmacology

Scientist IV, Pharmacology (Finance) Overview

The Scientist IV Pharmacology will play a key scientific role in designing, executing, and interpreting preclinical pharmacology studies to support the discovery and development of novel anti-infective therapeutics. This individual will contribute hands‑on scientific expertise across in vitro and in vivo pharmacology, pharmacokinetics, toxicology, PK/PD, efficacy studies, and data interpretation to support compound advancement from early discovery through preclinical development. The successful candidate will collaborate closely with cross‑functional partners in microbiology, medicinal chemistry, and clinical development to generate high‑quality pharmacology data that informs project strategy and decision‑making.

• Design, develop, optimize, and execute in vitro, ex vivo, and in vivo pharmacology studies to evaluate pharmacokinetics, efficacy, safety, and pharmacodynamic response of anti‑infective drug candidates.
• Analyze and interpret pharmacology, pharmacokinetics, toxicology, efficacy, PK/PD, and biomarker data to guide compound selection, dose rationale, and project progression.
• Contribute to study design for pharmacokinetic, toxicology, and efficacy models, including selection of appropriate models, endpoints, dosing regimens, controls, and statistical approaches.
• Prepare study protocols, technical reports, data summaries, presentations, and regulatory‑supporting documentation as needed.
• Work closely with internal project teams and external CROs to coordinate study execution, monitor progress, troubleshoot issues, and ensure high‑quality deliverables.
• Collaborate with microbiology, medicinal chemistry, and clinical development teams to integrate findings/results into broader drug discovery and development strategies.
• Maintain accurate, complete, and timely laboratory records and ensure work is conducted in accordance with applicable SOPs, safety requirements, and scientific best practices.
• Review scientific literature and emerging technologies to identify opportunities to improve pharmacology study design, assay performance, and translational relevance.
• Present scientific findings and recommendations to project teams, leadership, and external collaborators as appropriate.
• May mentor junior scientists or research associates, providing technical guidance, scientific feedback, and support for professional development.

Proficiency with commonly used data analysis and visualization tools; experience with pharmacokinetic and PK/PD modeling software is a plus. On occasion, may be asked to work overnight shift or weekend.

The base salary range for this full‑time position is $140,000 - $170,000. Individual pay is determined by several factors, which include but are not limited to: job‑related skills, experience, and relevant education or training. The range does not include the comprehensive benefits, bonus, long‑term incentive, applicable allowances, or any additional compensation that may be associated with this role.

Shionogi Inc. is an equal opportunity employer supporting individuals with disabilities and veterans. All qualified applicants will receive equal consideration for employment opportunities based on valid job requirements without regard to race, color, religion, sex (including pregnancy), marital status, national origin, age, ancestry, citizenship, disability, genetic information, status as a disabled veteran, a recently separated veteran, Active Duty Wartime or Campaign Badge Veterans, and Armed Forces Service Medal Veterans, or any other characteristic protected by applicable law.

It is the policy of Shionogi Inc. to undertake affirmative action for protected veterans and individuals with disabilities in compliance with all federal, state, and local requirements to recruit a diverse pool of protected veteran and individuals with disabilities applicants and to ensure that our employment practices are, in fact, non‑discriminatory. If you are qualified individual with a disability or a disabled veteran, you may request a reasonable accommodation if you are unable or limited in your ability to use or access this website to apply for a vacancy as a result of your disability.

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