Senior Research Associate, Analytical Development

Our Analytical Development team is growing and we're seeking a Senior Research Associate to participate in designing and executing experiments, as well as perform sample analysis utilizing HPLC, CE-SDS, iCIEF, and plate-based assays. These activities will support CMC, discovery, pre-clinical, and clinical development of existing and new lead candidates. This position will directly support the discovery of next-generation immune oncology drugs.

It is a hands-on position that requires effective communication and documentation of results to enable the advancement of novel research molecules toward development of clinical candidates, which will ultimately lead to late-stage development and commercialization. Ideal applicants will be agile and highly driven, collaborative, team-oriented, possess excellent communication and organization skills, and carry a strong commitment to excellence.

• Perform HPLC and UPLC assays with minimal supervision including SEC and RP.
• Execute CE-SDS and iCIEF analysis for novel protein therapeutics and contribute to method optimization, qualification, and lifecycle management.
• Perform ELISAs for potency assessment.
• Perform DLS/SLS analysis using an UNcle instrument and generate datasets that will be used for formulation development studies.
• Perform subvisible particulate matter analysis by HIAC.
• Perform formulation development studies and execute clinical in-use stability studies, transfer formulation knowledge internally.
• Design, conduct, analyze, interpret, and report laboratory experiments; summarize results for meetings and regulatory filings.
• Write and manage SOP's and test methods.
• Manage and maintain required reagents, laboratory environment, and equipment needed to carry out assignments.
• Draft development reports, method qualification protocols, and method qualification reports
• Prepare presentations for team meetings.
• Work closely with team leaders to complete highest priority work to reach goals and milestones.
• Other duties as assigned.

• Bachelor's degree and 4-6 years of relevant industry experience or a master's degree with 3-5 years of relevant industry experience.
• Strong benchtop skills, experience with analysis of protein biologics and peptides.
• Proficiency with HPLC and UPLC assays; at least 3 years of experience is required. SEC and RP are desired.
• Experience with protein characterization techniques including CE-SDS, iCIEF, or related electrophoretic methods is preferred.
• Experience performing ELISAs is desired but not necessary
• Experience supporting analytical method qualification, comparability, stability, or formulation development studies is preferred.
• Demonstrated ability to analyze complex datasets, identify trends, troubleshoot experiments, and communicate scientific conclusions effectively.
• Ability to perform routine testing and to follow SOPs in a highly accurate and reproducible manner.
• Desire and ability to learn new technologies and explore new approaches to innovate.
• Training on project specific assays and ability to train others.
• Proven experience with writing and maintaining SOPs.
• Demonstrated ability to maintain accurate, complete, and contemporaneous experimental records in ELN systems in accordance with Good Documentation Practices (GDP).
• Ability to work independently; anticipates and solves problems in a proactive fashion.
• Must have excellent computer skills, and proficiency with Microsoft Excel and PowerPoint are required.
• Good oral and written communication skills a must.
• Excellent team player.

$95,000 - $108,000 a year

In addition to a competitive base salary ranging from $95,000 to $108,000, we offer stock options, restricted stock units, a stock purchase plan (ESPP) and a…