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Principal Research AI Innovation Lead

Job in San Diego, San Diego County, California, 92189, USA
Listing for: Bristol Myers Squibb
Full Time position
Listed on 2026-10-03
Job specializations:
  • Research/Development
    AI Evaluation, Data Scientist, Research Scientist
Salary/Wage Range or Industry Benchmark: 145000 - 176000 USD Yearly USD 145000.00 176000.00 YEAR
Job Description & How to Apply Below
Principal Research AI Innovation Lead

We are seeking a Principal Research AI Innovation Lead to design, prototype, and scale AI-enabled capabilities that accelerate scientific research. This role will work across Research, AI, data, product, engineering, and enterprise technology teams to identify high-value opportunities, build practical LLM-enabled solutions, evaluate scientific quality, and create reusable capability patterns that improve how research teams use AI. The ideal candidate combines hands-on AI product and prototyping experience with working fluency in drug discovery, translational science, or a related research domain.

They can assess whether an AI output is scientifically sound, appropriately grounded, and useful for real research decisions - not merely technically complete. They are comfortable engaging with scientists on topics such as target evidence, indication selection, biomarker interpretation, translational rationale, or clinical evidence, and equally comfortable partnering with AI engineers to turn those needs into scalable systems.

Key Responsibilities

Partner with scientists and research leaders to identify high-impact opportunities where AI can improve research speed, quality, consistency, traceability, and decision-making. Help shape multi-year GenAI strategies, lead work streams, and establish reusable building blocks - agentic frameworks, evaluation harnesses, retrieval and grounding components, tool servers, prompt and policy libraries, and provenance infrastructure - on which research programs build. Architect and personally implement the agentic system-of-systems that executes complex, long-horizon scientific workflows across research, including target evidence assembly, indication rationale construction, biomarker interpretation, translational synthesis, literature and evidence triangulation, and decision support, with explicit attention to inter-agent coordination, state and memory management, verification, recovery from intermediate failure, and lifecycle governance of agents in production.

Establish the scientifically rigorous evaluation, benchmarking, and reliability standards that critical research AI systems expected to meet, including curated benchmark datasets, expert-reviewed reference standards, rubric-based assessments, hallucination and grounding metrics, calibration of uncertainty, longitudinal monitoring, regression gating in production, and the governance under which those standards are applied. Design mechanisms for incorporating expert feedback, scientific rationale, provenance, and research context into AI workflows so that systems and institutional knowledge improve over time.

Collaborate with engineering, data, IT, security, legal, vendor, and platform teams to ensure prototypes are designed with appropriate governance, integration paths, and scalability in mind. Communicate AI opportunities, risks, limitations, evidence quality, and results clearly to scientific, technical, and executive audiences. Stay current with emerging AI methods, tools, vendors, and industry practices, and assess where they can create practical value for Research.

Basic

Qualifications
  • Bachelor's Degree 8+ years of academic / industry experience
  • Master's Degree 6+ years of academic / industry experience
  • PhD 4+ years of academic / industry experience
Preferred Qualifications
  • Advanced degree, such as MS, PhD, PharmD, or equivalent experience in a scientific, computational, or AI-related field.
  • Direct experience in one or more research areas such as target identification and evaluation, indication expansion, drug repurposing, biomarker discovery, translational research, clinical evidence review, or portfolio decision support.
  • Ability to interpret scientific…
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