Sr. Scientist, Translational Medicine

Life at BMSAt Rayze Bio, every day is an opportunity to ignite meaningful change. As a wholly-owned subsidiary of Bristol Myers Squibb, Rayze Bio blends the nimble, pioneering spirit of an emergent biotech with the global expertise and resources of a leading innovator in oncology. Our mission is to develop transformative radiopharmaceutical therapies that offer new hope for patients living with cancer.

Here, you’ll join a multidisciplinary team where your ideas are valued, your expertise is amplified, and collaboration is at the heart of everything we do. From day one, expect to make an immediate impact—on our science, on our teams, and most importantly, on patients. Learn more about Rayze Bio:
Rayze Bio is a dynamic biotechnology company headquartered in San Diego, CA. Launched in late 2020 and recently acquired by Bristol Myers Squibb (BMS) as a wholly owned subsidiary, the company is focused on improving survival of people with cancer by harnessing the power of targeted radioisotopes. Rayze Bio will operate as a standalone entity within the BMS organization, maintaining its biotech culture with the opportunity to leverage the best-in-class oncology capabilities of BMS.

Rayze Bio is developing innovative drugs against targets of solid tumors. The lead asset, RYZ
101, is in Phase 3 testing for patients with gastroenteropancreatic neuroendocrine tumors (GEP-NETs), as well as earlier stage testing for patients with small cell lung cancer (SCLC).  Led by a successful and experienced entrepreneurial team, Rayze Bio aims to be the global leader in radiopharmaceuticals.

Job Description As a Senior Scientist, Translational Medicine supports clinical biomarker strategy for our oncology pipeline. This is an operationally focused, hands-on role for a scientist who has already worked directly on oncology clinical studies and understands what it takes to get biomarker samples from protocol design through data delivery. The successful candidate will partner closely with Clinical Development, Clinical Operations, Biostatistics, Regulatory, and Data Management to ensure biomarker sample collection, central lab and CRO/vendor oversight, and analytical assay execution are planned and delivered to the highest scientific and quality standards across one or more oncology clinical programs.

This role is best suited to a scientist with a strong foundation in clinical biomarker operations who is ready to grow into broader translational strategy leadership. The Senior Scientist will work under the guidance of the Translational Medicine Lead while independently owning day-to-day biomarker execution for assigned studies. As they gain experience, the role expands to include progressive ownership of biomarker strategy, as well as driving scientific data interpretation and actionable recommendations.

The position will require an ability to work effectively in interdisciplinary team settings. The role requires an ability and willingness to work with radioactive isotopes.

Job Responsibilities Essential duties and responsibilities include the following.  Other duties may be assigned.

Serve as the primary biomarker/translational medicine representative on clinical study teams for oncology trials.

Support end-to-end management of biomarker sample logistics, chain-of-custody, inventory tracking, reconciliation, and deviation resolution in collaboration with Clinical Operations and clinical sites.

Provide scientific review of biomarker components in protocols, ICFs, regulatory documents, laboratory manuals, and sample collection tables/kits to ensure biomarker objectives, sample types, collection procedures, and logistics are scientifically sound and operationally feasible in alignment with GCP/GCLP.Partner with Data…