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Business Head, AI Business & Operations

Job in San Francisco, San Francisco County, California, 94199, USA
Listing for: Twelve-Labs
Full Time position
Listed on 2026-09-12
Job specializations:
  • Business
    AI Business & Operations
Salary/Wage Range or Industry Benchmark: 180000 - 260000 USD Yearly USD 180000.00 260000.00 YEAR
Job Description & How to Apply Below

WHO WE ARE

Video is 90% of the world's data. Most of it is invisible to machines.

Twelve Labs builds the intelligence layer to change that. Our multimodal AI models understand video the way humans do — across sight, sound, and motion — and power production-scale AI workloads across media, entertainment, sports, security, and government.

We have raised over $200M from Silicon Valley's best VCs, including Index Ventures and NEA, and from leading enterprises like Nvidia and Amazon that are shaping the future of AI.

We are a global company, headquartered in San Francisco with offices in Seoul, New York, and London, and employees around the world. We believe the differences in our cultural, educational, and life experiences make our products stronger. Building technology that understands the world in all its complexity requires people who see it from every angle. We are looking for individuals who are driven by hard problems and want their work to matter.

Come build it with us!

ABOUT

THE ROLE

Twelve Labs spent years building the intelligence layer for video: shared infrastructure, multimodal video models, and an agent harness — the orchestration layer — that can understand and reason over video. Our vision for video superintelligence and pioneering work for large-scale video understanding allowed us to raise over $200M from Silicon Valley's best VCs like Index Ventures and NEA and leading enterprises like Nvidia and Amazon that are shaping the future of AI.

The next chapter for Twelve Labs is to turn that foundation into products that people can use without needing to understand the technology underneath.

We are hiring a Head of Applications to build that layer.

You will decide where Twelve Labs should play, find the first use cases where our technology creates a step change in the user experience, and turn those insights into products customers use and pay for. You will own the application layer from customer discovery through product, engineering, launch, adoption, and growth.

This is a builder-GM role. It is not a conventional product management job, a growth marketing job, or a large-team executive role. You should be comfortable talking with customers in the morning, working through a product or technical tradeoff in the afternoon, and assembling an exceptional team for the 0-to-1 journey that evening. Ideal candidates will come with 12+ years of experience across product and product leadership roles, preferably at early to mid stage software companies.

IN

THIS ROLE, YOU WILL
  • Set the strategy for Twelve Labs' application layer: which users and workflows to serve, what to build, and what not to build.

  • Find a focused wedge through direct customer discovery, rapid prototyping, and disciplined market testing.

  • Ship opinionated, AI-native applications for non-technical users on top of Twelve Labs' core models, agent harness, and shared infrastructure. Define application-specific evals, task-success criteria, reliability thresholds, human review, and launch guardrails.

  • Own the full outcome of the applications you ship, including activation, engagement, retention, monetization, and customer value. Shipping is the start, not the finish.

  • Build a fast learning loop between users and the product. Turn usage data and customer behavior into better workflows, interfaces, and model experiences.

  • Act as the demanding internal customer for our platform and model teams. Define the capabilities, APIs, latency, quality, and reliability the application layer needs without rebuilding the layers below it.

  • Partner closely with Design, Research and Engineering, Product, Commercial, Revenue, and Partnerships to take products from prototype to repeatable adoption. Work deeply with lighthouse customers, while converting what…

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