Director, Strategic Change Leadership Lead - Commercial, Medical, and Government Affairs; CMG

The Position

From the beginning, Genentech has been a team of highly dedicated, passionate individuals. We are a place where people are united around a single purpose and an ambitious vision. Together, we aspire to deliver ever better health outcomes for patients while lowering overall healthcare costs. Our goal is to compel the customer to act on behalf of their patients while showing great commitment to the rare disease community, whose support is key.

Utilizing innovative methods to identify patients who may benefit from treatment, we must take a highly strategic approach to patient access while assisting patients and their caregivers to navigate the healthcare system.

The Director, Strategic Change Leadership Lead, is a key member of the Strategy & Activation team, working across Commercial, Medical, and Government Affairs (CMG). This role drives the successful adoption of strategic initiatives and organizational capabilities by applying deep expertise in change leadership, organizational effectiveness, and team effectiveness.

As a trusted advisor to senior leadership, you will shape and execute change strategies that enable cross-functional alignment, innovation, and sustainable performance. You’ll foster a culture of resilience, adaptability, and continuous improvement, ensuring that change becomes a lasting competitive advantage.

• Serve as a strategic advisor and thought leader, leveraging a comprehensive understanding of the Commercial, Medical, and Government Affairs (CMG) functions to guide both transformational and incremental change.
• Balance strategic partnership with hands‑on execution, guiding teams through both the design and delivery of change.
• Conduct diagnostic assessments to identify change readiness, gaps, and opportunities, using these insights to develop, adapt, and implement strategic change management frameworks tailored to CMG's needs.
• Proactively identify potential risks, resistance points, and systemic patterns that may impact change initiatives across the CMG teams, developing targeted mitigation strategies to drive breakthrough results and long‑term sustainability.

• Lead the activation of CMG‑wide strategic initiatives that embed shared mindsets and behaviors, ensuring adoption and sustained impact with senior leadership support.
• Embed core behavior shifts that bring CMG’s Value to life by cultivating the Change Leadership Capabilities curriculum — focused on:
  • Role Modeling Change (responsibility and accountability, decision making, shifting from “me” to “we”)
  • Leading Change (creating psychological safety, managing productive conflict, addressing resistance)
  • Communicating Change (connecting hearts and minds, leveraging change accelerators).
• Coach senior and people leaders to strengthen these capabilities and lead change with confidence.

• Build and maintain strong relationships with senior leaders, department heads, and key stakeholders across the CMG teams to ensure alignment and buy‑in for change initiatives.
• Actively partner with Learning & Skill Development (L&SD), People & Culture (P&C), and Communications partners to manage the sequence and flow of information, training, and accountability.
• Leverage an indirect network of change champions across the organization to scale change actions and narratives and support change adoption and sustainability.

• Monitor the effectiveness of change management initiatives, track progress against metrics, and provide regular updates to senior leadership, demonstrating business impact.
• Establish mechanisms for continuous improvement, capturing lessons learned, feedback, and…