Chief of Staff

Probably Genetic is changing the lives of patients living with severe, complex diseases. Our data platform is used by drug developers and patient advocacy groups to develop and launch treatments for these patients. Our technology discovers untigen diagnosed patients online, analyzes their disease state using machine learning and at-home testing, and enables compliant communication with patients. In doing so, we help patients access diagnoses, clinical trials, and treatments as early as possible.

We are a tight-knit group of hard-working, ambitious problem solvers united by a mission greater than ourselves. We do well by doing right by patients. We are developing some of the most cutting-edge solutions in healthcare, and our roadmap is packed with innovations in bioinformatics, AI, and drug development. We have built a lean, all-star team to help us bring our vision to life, and we want you to be a part of it.

Probably Genetic has raised multiple rounds of funding from Silicon Valley’s best investors, including Threshold, Khosla, and Y Combinator, and offer competitive salaries, comprehensive benefits, and meaningful early stage equity.

We are at an inflection point. With a Series B on the horizon and a growing portfolio of partnerships with drug developers and patient advocacy groups, we need a Chief of Staff who can operate as a true right hand to the Founder and CEO — someone who runs toward complexity, brings structure to ambiguity, and holds the highest standards of craft and detail.

You will own high-stakes initiatives, manage venture fundraising end-to-end alongside the CEO, and serve as a force multiplier across the leadership team. If you have thrived in fast-moving, dynamic environments and want your work to directly improve patient outcomes, this is the role for you.

Venture fundraising & existing investor relations (20%)

• Own the end-to-end venture fundraising due diligence: materials, data room, investor outreach, pipeline management, and follow-through

• Serve as the primary point of coordination between the CEO and prospective and existing investors

• Prepare board meeting materials, manage the board cadence, and ensure follow-ups are tracked and closed

• Draft investor updates, pitch narratives, and other strategic communications with precision and clarity

CEO leverage, strategic through partnership & cross-functional execution (40%)

• Reduce CEO time on operational overhead by 30%+ by owning recurring processes, decision tracking, and stakeholder communication

• Lead cross-functional projects that span multiple teams, ensuring clarity of ownership, timelines, and outcomes

• Identify bottlenecks across the organization and build scalable processes to address them before they become problems

• Prepare the CEO for key meetings with background briefs, talking points, and follow-up documentation

Strategic external communications (40%)

• Own end to end preparation and execution for quarterly board meetings and mid-quarter check-ins

• Draft external communications on behalf of the CEO, including company-wide updates, partner communications, and thought leadership via a variety of social channels

• Ensure data and messaging is consistent and reflects the company's mission and values by creating a consistent framework for use by CEO and broader Leadership Team

We are looking for a few specific things that will help you succeed in this role:

• 8+ years of experience, with a strong foundation in management consulting (McKinsey, BCG, Bain, or equivalent) and subsequent operating experience at a high-growth startup

• Prior experience supporting or managing a fundraising process (Series A>D ideally); demonstrated understanding of investor relations and venture…