Associate Director, Clinical Data Management

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS‑addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

This position has a key role in the day-to-day management of Clinical Data Management (CDM) activities. It includes timely and professional management of clinical trial data for all relevant phases, representation of Revolution Medicines (Rev Med) CDM in Clinical Team meetings, and close collaboration with other functional leaders to ensure clinical trial success. The role defines project-level data management strategy, identifies requirements for capturing and processing clinical data ensuring accuracy, consistency, and completeness, manages external vendors providing clinical data, and performs data management tasks according to strict quality standards—including SAE reconciliation, third‑party vendor data reconciliation, medical coding processing, protocol deviation collection, and query management to identify errors and inconsistencies and ensure their resolution.

The position also provides CDM oversight of outsourced and partner‑resourced clinical trials, including scoping trials, project management, relationship management, approval of deliverables, and coordination of internal reviewers.

• Plans, coordinates, and manages CDM tasks for clinical studies.
• Participates and reviews CRO proposals.
• Acts as primary liaison with CROs, third‑party data vendors, and EDC vendors.
• Reviews clinical protocols and cross‑functional plans.
• Serves as primary reviewer or author of case report forms (CRFs) and CRF completion guidelines.
• Oversees and participates in all aspects of EDC database development, testing, maintenance, and lock/unlock.
• Ensures Data Management Plans are followed throughout the studies.
• Sets and manages Data Management project timelines.
• Provides comprehensive status updates to project team members.
• Addresses data issues identified by cross‑functional team members, accountable for external data vendor documentation, management, and reconciliation.
• Assists in defining and creating data listings, summary table validation, data specifications, and processes data transfers in preparation for statistical review and data management audit.
• Implements data standardization and maintains data model across projects.
• Directly manages and mentors internal data management team members.
• Leads department initiatives such as development of SOPs.
• Other duties as assigned.

• MS, BS/BA with 12+ years of related experience or other suitable qualification with relevance to the field.
• Direct experience designing and running early‑stage clinical trials.
• Knowledge of and experience with databases, standards, medical terminology, medical coding dictionaries, quality control processes, and auditing procedures.
• Good working knowledge of ICH, FDA, and GCP regulations and guidelines.
• A demonstrable record of strong leadership and teamwork.
• Thrives in a collaborative team setting and is driven by a desire to deploy innovative approaches and technologies in a high‑energy environment.
• Excellent written and verbal communication skills.
• Demonstrated ability to multi‑task, prioritize options, anticipate challenges, and execute on goals as a member of an interdisciplinary team is extremely important.

• Experience working within the biotechnology or pharmaceutical industry.
• Deep experience supporting oncology clinical trials, including hands‑on involvement with the operational and data‑related complexities unique to oncology studies.

The base pay salary range for this full‑time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be…