Application Administrator II

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development.

As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Application Administrator will work with the Senior Manager, Identity & Applications in the administration, configuration, integration, and ongoing support of enterprise collaboration platforms and enterprise applications that enable employees to work securely and efficiently. This role will partner closely with business stakeholders and ISDI teams to translate requirements into scalable application solutions, improve workflows, maintain strong access governance, and deliver a reliable user experience across the application portfolio.

Reporting to the Senior Manager, Identity & Applications, this role requires a hands-on, customer-focused administrator who can balance day-to-day operational support with platform improvements, automation, documentation, and lifecycle management in a fast-paced, regulated environment.

Key responsibilities include:

• Administer, configure, and support enterprise applications to ensure optimal performance, availability, security, and user experience.
• Manage application lifecycle activities, including implementation, upgrades, patching, testing, troubleshooting, monitoring, release coordination, and vendor support.
• Serve as an escalation point for complex application issues, perform root cause analysis, and drive issues through resolution while communicating status to stakeholders.
• Monitor application health, usage, licensing, and service performance; recommend improvements that increase reliability, adoption, and value.
• Maintain application roadmaps, support models, system inventories, ownership records, and lifecycle documentation.

• Administer collaboration, content management, and file-sharing platforms such as Egnyte, SharePoint, Teams One Drive, Atlassian Confluence & Jira, and Simpplr.
• Apply and enforce Rev Med security policies for permission management, content administration, information architecture, retention, governance, and external collaboration.
• Manage and enhance enterprise intranet portals, including page design, navigation, publishing workflows, audience targeting, and content owner support.
• Train and advise end users and content owners on collaboration tools, functionality, governance standards, and best practices.

• Manage user provisioning, deprovisioning, role-based access controls (RBAC), privileged access, and periodic access reviews across enterprise applications.
• Implement and support Single Sign-On (SSO), SCIM provisioning, Conditional Access policies, directory synchronization, and identity integrations using Microsoft Entra , Okta, Active Directory, LDAP, and related services.
• Partner with Information Security and application owners to enforce least-privilege access, segregation of duties, secure configuration standards, and audit readiness.
• Support monitoring, auditing, compliance, and security controls for enterprise applications, including systems…