Senior Manager, Project Management

Position: (Senior) Manager, Project Management
About us:

Braveheart Bio is a Bay Area-based biopharmaceutical company pioneering best-in-class therapies for cardiovascular disease. Our lead program is a next-generation myosin inhibitor, licensed from Hengrui Pharma, being developed to transform the treatment of hypertrophic cardiomyopathy (HCM)-the most common inherited cardiac disease.

Currently in Phase 3 clinical development in China for the more common obstructive form of HCM, our candidate has demonstrated a compelling clinical profile that may position it as a best-in-class therapy with meaningful differentiation.

With a proven leadership team, a strong financial foundation, and a high-value late-stage asset, Braveheart Bio represents an outstanding opportunity for ambitious, mission-driven professionals to make a tangible impact in a high-profile and rapidly evolving therapeutic area.

The role:

The Manager/Senior Manager of Project Management will play a central role in driving the planning, coordination, and execution of Braveheart's clinical development activities. This individual will work closely with functional leaders and team members to develop integrated development plans, anticipate risks, and keep projects moving efficiently toward key milestones. As a core facilitator of team operations, this role blends strategic project planning with hands-on execution, ensuring timelines, deliverables, and day-to-day coordination remain on track in a fast-paced, growth-oriented biotech environment.

The Manager/Senior Manager will structure project work, organize team forums, ensure clear information flow across functions, and bring disciplined follow-through to complex work streams. This role will also contribute to budget planning, operational tracking, and the evolution of project management best practices across the organization.

Key responsibilities:

Project Leadership & Execution

• Manage one or more clinical-stage projects, partnering with functional leaders to define project goals, integrated development plans, and key deliverables

• Create, maintain, and continuously update detailed project timelines (e.g., Gantt charts, trackers, dashboards), identifying critical path activities, dependencies, and resource constraints

• Monitor progress against plans; proactively identify risks, delays, or issues and recommend practical mitigation strategies and next steps

• Drive disciplined follow-up on action items and ensure accountable owners deliver on commitments

Team Operations & Cross-Functional Coordination

• Chair and support project team meetings, including agenda development, facilitation, preparation of high-quality meeting minutes, and tracking of decisions and action items

• Schedule, organize, and facilitate cross-functional sub-team meetings and ad-hoc working groups in partnership with functional leaders

• Ensure consistent, accurate flow of information across functions (Clinical, Regulatory, R&D, CMC, Finance, and others) to maintain alignment on priorities, timelines, and dependencies

• Serve as a central point of coordination to keep teams aligned and project execution moving forward

Project Reporting, Documentation & Planning

• Prepare project materials, summaries, and status updates for internal stakeholders and leadership forums

• Coordinate and draft monthly project status reports and other program-level updates

• Produce clear, concise timeline visuals and presentation materials to support team discussions and leadership decision-making

• Maintain organized, version-controlled project documentation that serves as a single source of truth for teams

Budget, Resource & Operational Support

• Interface with Finance and functional leaders to support budget planning, tracking, and forecasting

• Assist with resource planning, vendor coordination, and operational tracking as projects evolve

• Identify operational gaps or execution bottlenecks and propose practical, scalable solutions

Process Improvement & Startup Readiness

• Contribute to the development and refinement of project management best practices, tools, templates, and processes

• Operate effectively in a fast-paced, startup environment characterized by evolving priorities, limited structure, and ambiguity

• Demonstrate comfort working with imperfect information while maintaining disciplined execution and accountability

• • Bring a proactive, problem-solving mindset with a hands-on, roll-up-your-sleeves approach

Required experience & skills:

• Bachelor's degree in physical or life sciences or a related discipline; advanced degree or MBA preferred
• At least 8 years of biotechnology or pharmaceutical industry experience with a bachelor's degree, or at least 6 years with a master's degree
• Direct, hands-on experience in project planning, execution, and management across complex, cross-functional programs
• Strong proficiency with project management methodologies and tools (e.g., Smartsheet, MS Project, Asana, , or similar)
• Highly organized with exceptional attention to detail and strong analytical and problem-solving skills
• Excellent written and verbal…