Postdoctoral Scientist- Gonzalez Lab

Primary Work Address: 1550 4th Street, Suite 190, San Francisco, CA, 94158‑0724

The Gonzalez Lab at UCSF is seeking an energetic, curious, and driven Postdoctoral Scientist interested in systems neuroscience to join our research team. The Gonzalez lab focuses on identifying the fundamental mechanisms by which neurons process information and control behavior in mice and songbirds. We place particular emphasis on advanced optical approaches, including multiphoton microscopy, Bessel‑beam imaging, and closed‑loop patterned stimulation, to record and manipulate neuronal activity in behaving animals with high spatiotemporal precision.

By combining these cutting‑edge optical methods with electrophysiology and quantitative behavioral paradigms, we aim to uncover how neural circuits control complex motor behaviors and how their breakdown contributes to disorders of speech and movement. Our multidisciplinary approach integrates tool development with molecular, cellular, and systems neuroscience.
For more information, visit www.gonzalez‑

• Internal error correction mechanism of motor circuits.
• Integration of visuo‑acoustic sensory feedback during vocal behaviors.
• Memory and learning during offline periods (sleep).
• Long‑range neuronal communication and stroke.
• Brain‑machine interfaces to enhance learning and performance of complex behaviors.

• Programming and data analysis (MATLAB, Python, etc.)
• Optics and engineering (machining CNC/3D printing).
• Lab animal husbandry and surgical approaches (cranial implants, intracranial injections).
• Behavioral testing in animals.
• Electrophysiology, calcium imaging, microstimulation.
• Histology (vibratome, cryostat, microtome, antibody staining).

• A Ph.D. in neuroscience, bioengineering, or related field of science.
• Advanced experience in coding and analysis of large multimodal datasets.
• Ability to learn quickly and to work both independently and as part of a team.
• High level of research integrity and motivation.
• Positive attitude with a problem‑solving, resilient approach.
• Resourcefulness in overcoming challenges, and the ability to adapt and thrive in a fast‑paced environment.
• Willingness to fully participate in lab and departmental activities, to positively engage with other team members and promote their success (e.g., by reviewing manuscripts, participating in practice talks), mentor junior colleagues, and contribute to an inclusive and productive research climate.

We provide a competitive compensation package, comprehensive health and welfare benefits, one‑on‑one mentorship with the PI and daily discussions, opportunity to work in multiple animal models of motor behavior, exposure to cutting‑edge scientific research and opportunities for professional development, authorship on independent and collaborative scientific publications, and opportunities to attend domestic conferences in addition to departmental and HHMI retreats to present scientific findings.

Being part of the larger scientific community at UCSF.

Minimum: $70,000.00 – Midpoint: $80,500.00 – Maximum: $91,000.00 (annual).

Remaining in a normal seated or standing position for extended periods; reaching and grasping by extending hand(s) or arm(s); dexterity to manipulate objects with fingers (e.g., using a keyboard); communication skills using the spoken word; ability to see and hear within normal parameters; ability to move about workspace; ability to move materials weighing up to several pounds (such as a laptop computer or tablet).

Persons with disabilities may be able to perform the essential duties of this position with reasonable accommodation. Requests for reasonable accommodation will be evaluated on an individual basis.

We are an Equal Opportunity Employer. We use E‑Verify to confirm the identity and employment eligibility of all new hires. Howard Hughes Medical Institute (HHMI) is an independent, ever‑evolving philanthropy that supports basic biomedical scientists and educators with the potential for transformative impact. We make long‑term investments in people, not just projects, because we believe in the power of individuals to make breakthroughs over time.

Applicants have rights under federal employment laws.