Clinical Operations

About the Role

You’ll work closely with the founders and a small team from MIT, Harvard Medical School, Baker Lab, and Radical Numerics.

We are looking for speed and rigor, coupled with excitement, drive and a strong work ethic. In an early-stage environment, we value people who can bring clarity to open-ended problems, take ownership of the next steps, and follow through with energy.

Capable Labs is a place for ambitious, high-integrity people who want to become dramatically better. You will be surrounded by people who care intensely about the work, get close feedback from the people making scientific and company-defining decisions, and have room to own increasingly important problems.

We believe excellent work should be met with meaningful reward, ownership, and trust. Responsibility is earned through contribution, not title alone: anyone who demonstrates the judgment, rigor, and follow-through to move important work forward can earn meaningful scope.

• Negotiate vendor timelines, scopes, and budgets with strong judgment. When a vendor quotes a long timeline, you can pressure-test the assumptions, identify faster alternatives, and improve execution without compromising quality or rigor.

• Build strong relationships with investigators, site staff, coordinators, vendors, and external experts so Capable becomes a preferred partner.

• Anticipate operational bottlenecks before they become delays, including slow contracting, weak enrollment, unclear responsibilities, poor site communication, data lag, sample handling risks, vendor handoff issues, or protocol ambiguity.

• Work closely with founders, scientists, clinicians, regulatory advisors, and external partners to design studies that produce credible, decision-grade human data.

• Identify, evaluate, and manage clinical trial sites, labs, manufacturers, pharmacies, IRBs, and other vendors needed to run fast, rigorous studies.

• You have successfully led multiple clinical trials from site activation through execution, data delivery, and closeout. Ideally, you have also helped bring a therapy through clinical development to approval or market.

• You are organized and execution-oriented, helping keep studies moving by following up on site activation, vendor communication, contracts, patient visits, sample shipments, and expert input when needed.

• You are excellent with people, able to build trust with investigators, coordinators, vendors, and internal teams while still holding a high bar.

• You are skilled at evaluating vendor timelines, budgets, and scopes, can tell when assumptions need to be challenged, negotiate practical changes, and find faster or better alternatives.

• $135,000-$300,000 salary, plus equity options with an implied current value of approximately $50,000-$200,000 before exercise cost, taxes, dilution, and liquidity risk.

• Compensation will depend on the skills, experience, and scope of impact you bring. If your background, experience, or compensation needs fall outside this range, we are still open to a conversation based on the scope and impact you could bring.

• $500+ monthly wellness budget for training, supplements, coaching, recovery, or other tools that help you perform at your best.

• Healthcare:
  We offer a broad range of medical, dental, and vision coverage options, with Capable covering 100% of the base policy.

• You will also have access to HSA, FSA, and 401K plans.

• Healthy dinners with the team are provided daily.

• We support visa sponsorship where appropriate, including O-1, H-1B, J-1, TN, and other employment-based pathways. Our team is already international, with members from Canada, Pakistan, Germany, Austria, Switzerland, China, India, and the United States.

Our process is fast, transparent, and personal. We care about getting to know the person behind the application.

• Initial application

• First phone screen

• Second phone screen

• In-person work trial in San Francisco: designed to give both sides a realistic sense of working together. Get to know the founding team!

Curious but not sure? Apply anyway. It takes 5 minutes, and you do not need to be actively job searching to start a conversation.

Some of the best people do not map perfectly to a job description. If this sounds like a place where you could do important work, we would like to hear from you.

And if someone exceptional comes to mind, send them our way here. We read every referral carefully, and if your referral joins Capable, we’ll send you a thank-you bonus.