Senior Director Clinical Biomarkers, BioPharma Business Development

Senior Director Clinical Biomarkers, Bio Pharma Business Development

The Senior Director Clinical Biomarkers, Bio Pharma Business Development will provide strategic, scientific, and organizational leadership across a broad oncology diagnostics portfolio. This executive will be responsible for defining and advancing biomarker and translational medicine strategies across early- and late-stage Bio Pharma collaborations in support of Natera's strategic goals.

The ideal candidate will bring deep expertise in oncology drug development, biomarker strategy, and translational research, with experience spanning Phase 1–3 studies and multiple therapeutic modalities, including immunotherapy, targeted therapy, and antibody-drug conjugates.

• Lead translational medicine and clinical biomarker strategy across oncology programs within and beyond the Bio Pharma BD portfolio.
• Define and oversee biomarker plans supporting late-stage development in solid tumors within the Bio Pharma space (Pharma Lab Services, BD partnerships) including assay strategy, translational endpoints, data generation, data interpretation, publication planning, and regulatory filing support.
• Partner closely with clinical development, bioinformatics, medical affairs, regulatory, diagnostics, and commercial teams to ensure assay development portfolio and biomarker strategies are aligned with overall Bio Pharma BD needs.
• Work with external partners on their Natera-supported translational research efforts to help them leverage Natera capabilities to optimize the value of their projects: these may include identifying novel targets, characterizing resistance mechanisms, developing novel predictive biomarkers and next-generation clinical tools, including blood-based biomarkers, digital pathology, radiomics, and AI/ML-enabled approaches.
• Support development and lifecycle strategies that enable successful product differentiation, launch readiness, reimbursement, and broader clinical adoption.

• Contribute to study design and evidence-generation plans that support our Bio Pharma efforts across BD, Pharma Lab Services, and internal R&D.
• Work with the RWD, AI, and bioinformatics teams to develop use cases for existing data and build out new concepts for new data types as they are created.
• Apply translational insights to inform patient selection, development decisions, and clinical differentiation strategies for our customers.

• Establish and lead strategic collaborations with Bio Pharma partners, academic institutions, cooperative groups, scientific consortia, and key opinion leaders.
• Represent the company in external scientific and clinical initiatives that shape the future of biomarker-enabled oncology development.
• Build productive external partnerships that accelerate innovation, evidence generation, and adoption of novel translational approaches.

• Serve as a visible scientific leader through publications, invited presentations, advisory participation, and broader thought leadership in oncology and precision medicine.
• Maintain strong credibility in the external scientific community, with the ability to engage effectively with academic leaders, consortia, and industry partners.
• Contribute to the company's scientific reputation through high-impact external presence and publication strategy.

• Advanced degree in a relevant scientific discipline;
  PhD, MD, DVM, or equivalent strongly preferred.
• 15+ years of relevant experience in translational medicine, clinical biomarker development, oncology drug development, or related fields.
• Significant experience in biomarker-driven clinical development and medical affairs across early- and late-stage oncology programs.
• Demonstrated success in building external scientific relationships and representing organizations in high-profile external settings.
• Strong record of scientific leadership, cross-functional collaboration, and strategic execution.

The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.

Remote USA

$248,100 - $310,100 USD

Compensation & Total Rewards This range reflects a good-faith estimate of the base pay we reasonably expect to offer at the time of hire. Final compensation will vary based on experience, qualifications, and internal equity considerations. This position is also eligible for additional compensation and benefits through Natera's robust Total Rewards program, including:
Annual performance incentive bonus Long-term equity awards Comprehensive health benefits (medical, dental, vision) 401(k) with company match Generous paid time off and company holidays Additional wellness and work-life benefits