Director, Biotherapeutics Discovery

Biologics Discovery Leader

On Site - South San Francisco.

At Biogen, we are committed to discovering, developing, and delivering innovative therapies for people living with serious neurological and immunological diseases. In this role, you will lead biologics efforts for Biotherapeutics Discovery at Biogen's West Coast Hub in South San Francisco. You will drive cross-functional research and portfolio programs, shape the strategy around tomorrow's way of discovering biological drugs, and advance discovery innovation in close partnership with colleagues across the broader Research organization including key teams in Cambridge, MA.

· Lead and develop a high-performing team while advancing biologics technologies and platform innovation aligned with portfolio priorities

· In strong partnership with the Cambridge, MA team, support antibody discovery, engineering, optimization, and candidate selection strategies across discovery programs

· Evaluate external innovation opportunities and help shape adoption of next-generation biologics capabilities

· Contribute to molecular design strategies, including multi-specifics, novel formats, affinity tuning, epitope targeting, and develop ability assessments

· Partner across functions, including protein engineering, computational design, pharmacology, translational sciences, Immunology, and Neurology, to initiate and shape discovery campaigns

· Guide modality and candidate selection based on target biology, mechanism of action, and translational considerations, and support early target assessments that test key biological hypotheses

· Coach and mentor scientists, fostering technical growth, scientific excellence, and strong collaboration

· Build an inclusive culture of innovation, accountability, and continuous learning

You are a strategic and collaborative scientific leader with deep expertise in biologics discovery and antibody engineering. You bring strong scientific judgment, thrive at the intersection of biology and molecular design, and are motivated by solving complex problems in partnership with cross-functional teams.

You are also a strong people leader who is passionate about developing talent, enabling collaboration, and building high-performing teams that deliver meaningful scientific impact.

· Ph.D. in biochemistry, immunology, molecular biology, or a related scientific discipline

· 12+ years of industry experience in biologics drug discovery, including leadership of antibody discovery and optimization programs

· Proven success advancing molecules from discovery through candidate nomination

· Deep expertise in antibody engineering, molecular design, and biologics discovery workflows

· Experience across biologics modalities, including bispecifics, fusion proteins, and conjugates

· Demonstrated experience leading and developing scientific teams

· Strong track record of cross-functional partnership, including collaboration with disease biology teams

· Excellent communication and leadership skills, with the ability to influence scientific direction across teams and sites

Additional Qualifications

· Experience in translational immunology and a strong understanding of immunology disease biology

· Experience partnering with Immunology or Neurology research teams

· Background in early target assessment and discovery campaign initiation

· Experience identifying and sourcing external innovation through collaborations with CROs, biotech companies, or academic groups

· Familiarity with computational design or AI/ML applications in biologics discovery

Job Level: Management

Additional Information

The base compensation range for this role is: $-$

Base salary offered is determined through an analytical approach utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity.

Regular employees are eligible to receive both short term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward recent achievements and recognize your future potential based on individual, business unit and company performance.

In addition to…