Lab Technician

Eon Scientist Opportunity

Eon is building large-scale connectomic data collection systems to enable safe and scalable brain emulation technology. Our mission is to help bring human intelligence into the digital age.

We are looking for a scientist to help build robust tissue processing and expansion microscopy pipelines for high-resolution volumetric imaging of mammalian brain tissue.

As the Lab Lead, you will be the backbone of Eon's tissue processing and lab operations. You will be responsible for overseeing day-to-day laboratory workflows, supporting the development and execution of robust tissue-processing pipelines, and ensuring that the team has the materials, tools, documentation, and operational systems needed to maintain high standards of quality, reproducibility, and throughput.

This role is ideal for a highly organized, hands-on individual with a strong foundation in laboratory operations, tissue processing, and workflow management. You should have a keen eye for operational efficiency, strong scientific judgment, and an eagerness to take ownership of complex, mission-critical processes.

As a core member of a fast-moving company, you will have the chance to contribute beyond a narrow job description. We value team members who take initiative, are eager to learn new skills, and are willing to wear multiple hats to help drive our broader mission forward. This is a role with real opportunity to make a tangible impact on Eon's core imaging workflows and the systems that support them.

Work Hours:

In-person full-time, Monday to Friday, standard business hours, with some flexibility required to support operations.

Lab Operations & Workflow Management:
Streamline and manage end-to-end laboratory workflows related to tissue processing, staining, expansion microscopy, and sample preparation. Ensure smooth execution, strong coordination across teams, and reliable handoff into downstream imaging workflows.

Lab Management & Supervision:
Take ownership of day-to-day lab operations, including maintaining lab organization, supporting team execution, managing priorities, and ensuring the lab adheres to safety, cleanliness, and quality standards.

Tissue Processing & Pipeline Support:
Lead and improve the processing, staining, and preparation of mammalian brain tissue for high-resolution volumetric optical imaging. Help develop robust and reproducible workflows that integrate cleanly into Eon's broader imaging pipeline.

Inventory & Procurement:
Manage and optimize inventory systems for reagents, consumables, antibodies, stains, and other critical supplies. Forecast needs, coordinate procurement, and ensure uninterrupted lab operation.

Equipment, Maintenance & Systems:
Oversee instrument upkeep, maintenance schedules, and day-to-day readiness of lab infrastructure. Support standardized equipment documentation, process consistency, and reliable system performance.

Documentation, SOPs & Process Standardization:
Maintain meticulous and organized records of protocols, experiments, workflow changes, and operational updates. Draft, refine, and maintain SOPs, work instructions, checklists, and training materials to support reproducibility, adoption, and long-term sustainment.

Cross-Functional Collaboration:

Work closely with researchers, animal teams, microscopy teams, and engineering teams to improve upstream and downstream pipeline performance. Clearly communicate progress, challenges, and process updates in a structured way.

Operational Tracking & Continuous Improvement:
Track workflow performance, process gaps, risks, and decisions. Produce clear summaries and basic metrics related to throughput, training coverage, SOP updates, and operational readiness. Help define more standardized future-state workflows as the lab scales.

Your work may include:

• Optimizing staining of large mammalian neural tissue for strong, reproducible signal quality
• Developing and improving expansion microscopy pipelines for large tissue samples
• Refining tissue processing methods to improve quality, consistency, and throughput
• Executing signal amplification strategies to improve signal-to-noise ratio
• Validating antibodies and other staining reagents for use in neural tissue
• Characterizing processed tissue using fluorescence microscopy and integrating samples into volumetric imaging workflows
• Collaborating across teams to improve upstream and downstream pipeline performance
• Developing new protocols for thick tissue staining, section handling, and whole-brain processing
• Managing reagent, consumable, and sample flow systems to support reliable lab execution
• Standardizing documentation, SOPs, and training materials to enable consistent adoption across workflows

We are looking for someone with strong scientific judgment, high agency, and deep comfort working in a fast-moving experimental environment.

You should be excited by the idea of building new workflows rather than just running established ones. The right…