Research Associate - Ramani Lab

Category

Science Lab / Area:
Ramani Lab

The Gladstone Institutes is a leading independent, not-for-profit research organization dedicated to improving human health through groundbreaking biomedical research and education. Our work spans neuroscience, cardiovascular biology, immunology, and stem cell biology, with a strong emphasis on understanding and treating disease. With approximately 600 team members, including world-renowned scientists and biomedical leaders, Gladstone fosters a collaborative and innovative environment. Located at the Mission Bay Campus in a state-of-the-art facility, we offer competitive salaries, comprehensive benefits, and the resources to empower individuals to maximize their potential and make a meaningful impact on global health.

The Ramani Lab at Gladstone Institutes is seeking a highly motivated Research Associate to support wet-lab research initiatives. The lab specializes in the development and application of cutting‑edge sequencing technologies to investigate transcriptional regulation at a genome‑wide scale. Research Associates will help build on recent studies focused on understanding chromatin fiber structure in the contexts of regulated transcription and DNA replication.

• Assist with lab organization, including reagent procurement and inventory management.
• Aid with the lab’s biochemistry pipeline for creating and characterizing chromatin in vitro through protein purification, molecular biology, and genomics data analysis.
• Generate single‑cell and single‑molecule sequencing libraries compatible with Illumina and Pac Bio sequencing platforms.
• Perform biochemical techniques such as protein purification and in‑vitro reconstitution of molecular processes.
• Conduct molecular biology experiments to create sequencing libraries for high‑throughput sequencing platforms.
• Develop and optimize molecular biology protocols, including barcoding, amplification, and processing of DNA and RNA from mammalian cells.
• Collaborate with team members to analyze and interpret sequencing data.

• B.S./B.A. degree in a relevant scientific field by the time of hire.
• Prior experience in protein purification and biochemistry.
• Applicants currently completing their degree may apply, but the degree must be conferred by the appointment start date.

• Experience with high‑throughput sequencing technologies, including Illumina, Pacific Biosciences, or Oxford Nanopore.
• Experience with molecular biological protocols.
• Familiarity with mammalian tissue culture techniques.
• Proficiency in bioinformatics or scripting languages such as UNIX, C++, Python, or R.

$28.35/hr ($58,968) – $32.67/hr ($67,949)

• Competitive salary and title commensurate with education and experience.
• Generous medical, dental, vision, retirement plan, paid vacation, commuter benefits, and access to free shuttle transportation.
• Healthy work/life balance with support to recharge and enjoy vibrant life outside of work.
• Respectful inclusive culture that values each member of its community.

Gladstone is committed to providing equal employment opportunities to all employees and applicants for employment without regard to race, color, sex, religion, national origin, ancestry, age, marital status, medical condition, physical or mental disability, veteran status, sexual orientation, or any other non‑job related characteristic. We make all employment decisions so as to further this principle of equal employment.