Senior Research Associate, Lipid Nanoparticle Formulation

Senior Research Associate, Lipid Nanoparticle Formulation (BH-399064)

Location South San Francisco, United States Sector Science & Research

Yoh is seeking a skilled and motivated Senior Research Associate, Lipid Nanoparticle Formulation to join our client’s Delivery Sciences team and support the development of lipid nanoparticle delivery systems for nucleic acid-based therapeutics. This laboratory-based role will focus on LNP formulation, downstream processing, analytical characterization, and process optimization for research and preclinical programs. The ideal candidate possesses a deep technical understanding of LNP assembly via various mixing methods, expertise in downstream purification, and hands‑on experience with advanced analytical characterization techniques.

Location: South San Francisco

Duration: 3+ month contract with ability to convert to permanent

Shift: M-F day shift

Pay: $45-60/hr DOE

Responsibilities:

• Prepare, purify, and characterize LNP formulations for nucleic acid delivery.
• Develop and optimize lipid compositions, formulation parameters, purification workflows, and analytical methods.
• Support LNP production at multiple scales for in vitro and preclinical studies.
• Collaborate with cross-functional research, product development, and preclinical teams to meet program requirements.
• Analyze complex experimental results and use the findings to guide formulation and process-development decisions.
• Anticipate future material and equipment needs, coordinate procurement, and help maintain laboratory readiness.
• Document methods, experiments, and results accurately in an electronic laboratory notebook.

Qualifications:

• Master’s degree in pharmaceutical sciences, biomedical engineering, chemical biology, or a related scientific discipline, with at least two years of relevant industry experience, or an equivalent combination of education and experience.
• Hands‑on experience formulating LNPs containing different lipid components for nucleic acid delivery.
• Experience with downstream purification methods such as tangential flow filtration, dialysis, ultracentrifugation, and sterile filtration.
• Experience with relevant analytical techniques, which may include DLS, chromatography-based methods, capillary electrophoresis, fragment analysis, osmolality, MALS, ELISA, and fluorescence‑based plate assays.
• Strong experimental documentation, troubleshooting, data interpretation, and cross‑functional communication skills.

Preferred Experience:

• Experience supporting preclinical or clinical‑stage drug product development.
• Familiarity with liver‑directed delivery or hepatocyte‑based models.
• Experience with LNP surface modification, bioconjugation, or the addition of targeting ligands.
• Familiarity with statistical analysis or data visualization using tools such as R or Python.

Estimated Min Rate
: $42.00

Estimated Max Rate
: $60.00

What’s In It for You?

We welcome you to be a part of the largest and legendary global staffing companies to meet your career aspirations. Yoh’s network of client companies has been employing professionals like you for over 65 years in the U.S., UK and Canada. Join Yoh’s extensive talent community that will provide you with access to Yoh’s vast network of opportunities and gain access to this exclusive opportunity available to you.

Benefit eligibility is in accordance with applicable laws and client requirements. Benefits include:

• Medical, Prescription, Dental & Vision Benefits (for employees working 20+ hours per week)
• Health Savings Account (HSA) (for employees working 20+ hours per week)
• Life & Disability Insurance (for employees working 20+ hours per week)
• Met Life Voluntary Benefits
• Employee Assistance Program (EAP)
• 401K Retirement Savings Plan
• Direct Deposit & weekly epayroll
• Referral Bonus Programs
• Certification and training opportunities

Note:

Any pay ranges displayed are estimations. Actual pay is determined by an applicant's experience, technical expertise, and other qualifications as listed in the job description.

Yoh, a Day & Zimmermann company, is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.

For California applicants, qualified applicants with arrest or conviction records will be considered for employment in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act. All of the material job duties described in this posting are job duties for which a criminal history may have a direct, adverse, and negative relationship potentially resulting in the withdrawal of a conditional offer of employment.

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.