Senior Research Associate

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Everyone Owns Achieving Our Inspiring Mission
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Altos Labs has been named one of the Top 3 Biotech Companies and ranked for the second year on the Forbes 2026 Best Startups in America list. At Altos, exceptional scientists and industry leaders from around the world work together to advance a shared mission. Our intentional focus is on Belonging, so that all employees know that they are valued for their unique perspectives.

We are all accountable for sustaining a diverse and inclusive environment.

An exciting opportunity is available for a Senior Research Associate (Contractor) to join the In Vivo Translational Sciences (IVTS) team within 3DS (Drug Discovery and Development Sciences) at Altos Labs. The Senior Research Associate will provide hands-on in vivo support across multiple programs, executing rodent studies from study initiation through completion. Responsibilities include dosing, in-life procedures, blood collection, necropsy, tissue collection and processing, and accurate study documentation to generate high‑quality data for project teams.

You will work closely with in vivo scientists, operational leads, and vivarium staff to plan and execute studies according to established protocols, timelines, and applicable IACUC and animal welfare standards. This role requires a broad and demonstrated in vivo skill set, including proficiency in multiple dosing routes, blood collection techniques, tissue harvest, necropsy, and accurate and timely record keeping.

The ideal candidate is a highly collaborative, detail‑oriented, and adaptable team member who can work effectively across multiple programs and priorities while maintaining a high standard of animal welfare, technical execution, and data quality.

Key Responsibilities:

In Vivo Study Execution

• Execute hands-on in vivo studies in rodents (primarily mice; rats as needed) under the guidance of the Operational Lead and in accordance with approved protocols and timelines.
• Perform dosing via multiple routes, including PO, IP, IV, and SC; experience with oropharyngeal and intratracheal administration preferred, with stereotactic/ICV surgery experience a plus.
• Perform in-life blood collection, including submental/submandibular and tail vein bleeds, as well as terminal cardiac blood collection.
• Perform necropsy and transcardiac whole-body perfusion, including tissue harvest, dissection, and tissue weighing. Experience with CSF collection is a plus.
• Perform basic sample processing, including snap-freezing, fixation, labeling, and sample transfer.
• Monitor body weight, clinical observations, animal health, welfare, and special diets, with appropriate documentation and escalation of concerns.
• Troubleshoot routine technical and operational challenges and communicate with scientists and operational leads to identify and implement appropriate corrective actions.

Study Planning, Logistics, and Documentation

• Partner with in vivo operational leads and scientists to plan and schedule study activities, including dosing, sample collection time points, and necropsies across multiple programs.
• Communicate effectively across teams to coordinate study activities, priorities, timelines, and sample needs.
• Accurately document all procedures, observations, and data in study sheets and electronic records, ensuring data integrity and traceability.
• Assist with organization and maintenance of in vivo work spaces, ensuring adequate supplies, reagents, and equipment readiness.

Animal Welfare,…