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Lead Principal Scientist, Oligonucleotide Design & Chemistry

Job in San Francisco, San Francisco County, California, 94199, USA
Listing for: Genentech
Full Time position
Listed on 2026-10-06
Job specializations:
  • Research/Development
    Research Scientist, Biotechnology, Drug Discovery, Biotech Research
Salary/Wage Range or Industry Benchmark: 143000 - 266000 USD Yearly USD 143000.00 266000.00 YEAR
Job Description & How to Apply Below

Genentech in South San Francisco seeks a Principal Scientist (Group Leader) to drive oligonucleotide modalities across drug-discovery programs. You will design, synthesize, purify, and characterize ASOs/siRNAs, mentor scientists, and partner with biology teams to enable rapid decision-making.

You are a scientific leader with a Ph.D. and 3+ years postdoc/industry experience, fluent in communicating complex concepts and advancing cross-functional initiatives.

We invite applications for the Lead Principal Scientist, Oligonucleotide Design & Chemistry position located in San Francisco, CA, United States.

For the Lead Principal Scientist, Oligonucleotide Design & Chemistry position at Genentech, we are reviewing applications now.

Step into the Lead Principal Scientist, Oligonucleotide Design & Chemistry role at Genentech in San Francisco, CA, United States and grow with us.

Please review the full job details above before applying.

If your experience matches this role, we encourage you to apply.

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