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Bioinformatics Engineer, Variant

Job in San Francisco, San Francisco County, California, 94199, USA
Listing for: LatchBio
Full Time position
Listed on 2026-06-07
Job specializations:
  • Software Development
    Data Scientist, Data Engineering
Job Description & How to Apply Below
As molecular data generation and frontier model intelligence grows, new approaches to data analysis are needed across the biotech industry. Latch is building intelligent, high performance agents for biological data analysis, empowering over 5,000 scientists across 150+ R&D labs to handle data from instrument-to-insights.

We're seeking a Bio Engineer for Genomics to join our genomics bench, working at the frontier of what artificial intelligence can achieve in biology.

About the Role

You will contribute to our technical approach to teaching agents how to understand and handle complex genomic data, working across end-to-end data analysis workflows from instrument outputs to real scientific decisions.

You will work as part of a team of software engineers and biologists building datasets to teach these agents to reason better across:
  • Sequencing QC → alignment & assembly
  • Variant calling & filtering
  • Clinical variant interpretation
  • Population genetics → algorithmic reasoning
Requirements
  • 5+ years hands-on experience with genomics or genetics data
  • Experience in drug mechanism of action studies using population genomics
  • Proficiency in Python and/or R
Compensation & Logistics
  • OTE 120k - 180k, performance based, based on individual's expertise
  • 100% premium covered Blue Shield platinum health plan
  • Free meals (lunch and dinner)
  • Waterfront office in China Basin, San Francisco
  • Full-time, in-person (can be remote)
Location: San Francisco, CA. In-person.
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