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Lead Platform Engineer

Job in San Francisco, San Francisco County, California, 94199, USA
Listing for: VSG Business Solutions LLC
Full Time position
Listed on 2026-08-21
Job specializations:
  • Software Development
    Backend Developer, Cloud Engineer - Software
Salary/Wage Range or Industry Benchmark: 200000 - 260000 USD Yearly USD 200000.00 260000.00 YEAR
Job Description & How to Apply Below
Position: LEAD PLATFORM ENGINEER

JOB Description :

Technical lead for the compute, data, AI, and security infrastructure that runs our sequencing operation.

You will own core services that orchestrate lab devices (robots, sequencers, on-prem Linux servers) and the data ingestion pipeline

Build cloud infrastructure and data pipelines to house, process, and deliver terabytes of sequencing data

Design infrastructure to orchestrate millions of bioinformatics tasks (queues, workflow orchestration, scheduling)

Build AI infrastructure and internal tooling to enable agentic systems:

  • Quality Scientist Agents - monitor operations end-to-end, surface anomalies, and intervene/escalate when quality or reliability issues appear
  • Logistics Agents - coordinate drivers around the world to move packages to labs and carriers
  • Bioinformatics Coding Agents - long-running agents for adaptive analysis of diverse sample types with unknown/shifting data distributions

This opportunity aligns with your focus on backend and infrastructure roles in San Francisco within the AI industry. You will be working with a top 1% hiring manager who maintains a streamlined three-step interview process, including a final call with the CEO.

Work experience
  • 8+ years of experience in platform/backend/infrastructure engineering
  • Must have impactful experience at a startup while it has scaled (ideally Seed - Series C)
  • Can design + build reliable distributed systems (queues, orchestration, state machines) and ship them to production
  • Led projects and mentored engineers on small teams
  • Former successful founder or founding engineer
Education
  • BS in CS, Engineering, Math, Physics or equivalent technical degree
Hard skills
  • Strong AWS orchestration (ECS, Batch, Step Functions) + Python backend work (FastAPI/Django)
  • Linux server administration and distributed task queues (Celery/SQS)
  • Experience building LLM/agent systems (tooling, evaluation, safety/permissions, prompt + workflow design)
Soft skills
  • Very hungry and wanting to take a step up in their career. Senior/Staff - >
    Lead engineer
Miscellaneous
  • Up to date with newest AI tooling
  • Genuine curiosity about biotech/science domains

strongly prefers candidates who completed their undergraduate (bachelor's) degree in the US, Canada, or Europe
,

TRAITS TO AVOID
  • Too senior and no longer an IC
  • Only experience is big tech that doesn't specialize in managing data at scale.
  • Not looking for career FAANG engineers.
  • International students coming from master's programs
  • Job hoppy (multiple stints of
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