Senior Director, Controller

Senior Director, Controller

Department: Corporate Development & Operations

Employment Type: Full Time

Location: San Mateo, CA

The role: Big Hat Biosciences is seeking a detail-driven, proactive, and analytical Controller to serve as Big Hat's senior accounting leader and architect of its finance infrastructure at a pivotal stage of growth. This role is for someone who enjoys solving complex accounting challenges, focuses on continuous process improvements, thrives in a fast-paced environment, and is a true builder. You will own the full accounting function, from close and financial reporting to technical accounting, equity, tax and compliance.

You'll also be designing and/or improving the systems, controls, and processes required for a future public-company operating environment.

The right candidate brings accounting experience from a high-growth biotech, pharma or life sciences company (with exposure to CRO accruals and R&D program cost tracking), hands-on Net Suite (or similar) implementation or migration experience, and the technical rigor to independently research and document complex GAAP positions. You are comfortable serving as the primary interface with external auditors, capable of building an internal Sarbanes-Oxley (SOX) Compliance control framework from the ground up, and ready to lead the company's transition off Quick Books as we scale.

• Serve as Big Hat's in-house technical accounting authority; research and prepare position memos on complex transactions, new GAAP pronouncements, and company-specific accounting policy decisions, analyzing and communicating risks and benefits effectively.
• Executes general ledger operations, leading financial close process to ensure accurate and timely US GAAP financial statements.
• Drive R&D accounting across CRO and vendor accruals, prepaids, and program-level cost tracking, bringing structure and visibility to one of the company's largest spend categories.
• Build and deliver financial reporting packages and board-level management decks; translate financial results and key metrics into clear narratives for executive leadership and the Board.
• Design, implement, and maintain a SOX compliance internal control framework scaled for a high-growth company, balancing rigor with operational practicality as the company grows.
• Lead audit readiness; drive clean, timely delivery of annual financial statement audits in accordance with GAAP.
• Manage federal, state, and local tax compliance in coordination with external advisors; lead R&D tax credit studies and other R&D-related tax matters.
• Evaluate and implement AI-enabled tools and finance technology, including procure-to-pay and close management tools, to reduce manual effort, improve auditability, and strengthen data integrity at scale.
• Own payroll administration and equity accounting and plan administration under ASC 718 (including stock-based compensation expense, 409A valuation support, cap table integrity, and related financial statement disclosures).
• Own Net Suite ERP implementation including processes and controls while maintaining segregation of duties.

• Bachelor's or Master's in Finance, Accounting or Business preferred. Active CPA license.
• 10+ years of professional experience in accounting, including 3+ years of experience in a public biotech company.
• Prior Controller or Assistant Controller experience at a venture-backed biotech or life sciences company strongly preferred.
• Strong command of US GAAP and technical accounting standards.
• Big 4 audit experience.
• Hands-on public company reporting experience; have personally prepared or reviewed Forms 10-Q and 10-K at a public company.
• Experience with CRO/CDMO contract accounting and accrual estimation.
• Hands-on experience with Net Suite or a comparable ERP, including comfort operating through a system migration.
• Familiarity with SOX/ICFR build-out in a pre-IPO environment.
• A track record of embedding AI tools to accounting and finance workflows.
• Experience managing and transitioning outsourced accounting or consultant relationships in-house.
• Demonstrated success in building and managing teams to achieve financial and business goals.
• Excellent communication skills, both written and verbal, with the ability to convey complex information to diverse audiences.
• Comfort with uncertainty and demonstrated ability to exercise sound judgment under tight timelines and independently determine appropriate action where precedent may not exist.
• Detail-oriented…