Senior Research Associate, Discovery Medicine
Listed on 2026-06-17
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Research/Development
Research Scientist, Immunology Research
Senior Research Associate, Discovery Medicine
Department: Discovery Medicine
Employment Type: Full Time
Location: San Mateo, CA
DescriptionThe role: Big Hat Bioscience is looking for a motivated and energetic Senior Research Associate with a strong background in Immunology, cell culture, flow cytometry and primary cell-based assays to support the characterization of our lead therapeutic candidates.
* At Big Hat we believe in titles that commensurate with skill set, relative organizational impact, and value contribution; more experienced candidates are encouraged to apply, with the understanding that responsibilities and title would adjust as appropriate.
Key Responsibilities- Drive the development of therapeutics by owning the functional characterization of therapeutic candidates.
- Plan, execute, and analyze TDCC, T cell activation, cytokine release, FACS, ELISA, ADCC, and other relevant functional assays.
- Perform isolation and culture of primary immune cells from blood or tissue.
- Inform program plans based upon experimental results and make relevant recommendations for program conceptualization and advancement.
- Keep detailed and organized records of experimental protocols and results.
- Proactively and independently interpret and present scientific findings.
- Collaborate and communicate across a diverse research team to successfully progress scientific goals.
- B.Sc. degree in cell biology, molecular biology, biochemistry, genetics, immunology, or a related field, with at least 3 years of relevant experience, including 1 year in industry.
- Hands‑on proficiency in standard immunology and cell biology techniques such as mammalian cell culture and multicolor flow cytometry.
- Previous experience with automation and high‑throughput assays desired.
- Scientific curiosity and problem‑solving abilities.
- A strong can‑do mentality and desire to thrive in a dynamic start‑up environment.
- The ability to communicate clearly and build open collaborative relationships.
The salary estimated for this position is $100,000 - $115,000 + bonus + options + benefits. Compensation will vary depending on job‑related knowledge, skills, and experience. Actual compensation will be confirmed in writing at the time of the offer.
What Big Hat Offers:
- Range of health insurance plan options through Anthem and Kaiser (monthly credit if benefit waived)
- Dental, and vision coverage through Guardian
- Additional well‑being benefits through Nayya, One Medical, Wagmo, Rula, and more
- 401(k) with company match
- DTO, two weeks of company‑wide shutdown, and 12 company holidays
- Paid parental leave
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