Research Associate I​/II, Production Lab Science San Mateo, CA

Research Associate I/II, Production

Department: Lab Science

Employment Type: Full Time

Location: San Mateo, CA

The Role: Big Hat Biosciences is seeking a self-motivated individual for a Research Associate I/II, Production, role to power our high-throughput, automated platform for antibody production and deep molecular characterization.

• Perform automated and manual high-throughput processing on the Big Hat platform, including DNA preparation, protein expression, and protein characterization.
• Contribute to the scaling up of Big Hat’s platform and production-grade data generation.
• Support Big Hat’s Platform Reagents & Assay Support (PRAS) function by contributing to in-house reagent manufacturing efforts.
• Execute experiments to optimize the performance efficiency of Big Hat’s platform.
• Keep a detailed record of all experiments using Big Hat’s documentation tools, and clearly communicate results and challenges.
• Collaborate on the creation of laboratory standard operating procedures (SOPs) for sample processing.
• Collaborate closely with Big Hat team members to identify, design, and implement critical process and operational improvements to production workflows and laboratory systems.
• Operate automated liquid handlers and analytical instruments to ensure all lab and platform operations run efficiently.

• BS in Biology or Chemistry, with 1+ year(s) of industry experience
• Experience in process execution, laboratory method development, optimization, and troubleshooting.
• Hands-on experience with, or interest in, automated liquid handlers (e.g. Hamilton, Open Trons, Tecan, Agilent systems). Experience with LIMS is a nice-to-have.
• Experience with molecular biology techniques and general lab practices.
• Efficient time management and ability to work on several projects simultaneously, in a dynamic start-up environment.
• Strong interpersonal skills and ability to effectively communicate with members of a multidisciplinary team.
• Excellent record keeping abilities to document experimental work and analytical data.
• Nice-to-haves include previous experience working with barcoding systems, inventory tracking, and experience with Google Workspace tools (Docs, Sheets, Slides, etc.)

The salary estimated for this position is $75,000 - $105,000 + bonus + options + benefits. Compensation will vary depending on job-related knowledge, skills, and experience. Actual compensation will be confirmed in writing at the time of the offer.

What Big Hat Offers:

• Range of health insurance plan options through Anthem and Kaiser (monthly credit if benefit waived)
• Dental, and vision coverage through Guardian
• Additional well-being benefits through Nayya, One Medical, Wagmo, Rula, and more
• 401(k) with company match
• DTO, two weeks of company-wide shutdown, and 12 company holidays
• Paid parental leave