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Research Associate I​/II, Production

Job in San Mateo, San Mateo County, California, 94403, USA
Listing for: BigHat Biosciences
Full Time position
Listed on 2026-06-27
Job specializations:
  • Research/Development
    Research Scientist, Biomedical Science, Biotechnology, Biotech Research
Salary/Wage Range or Industry Benchmark: 75000 - 105000 USD Yearly USD 75000.00 105000.00 YEAR
Job Description & How to Apply Below

Research Associate I/II, Production

Big Hat Biosciences is seeking a self-motivated individual for a Research Associate I/II, Production, role to power our high-throughput, automated platform for antibody production and deep molecular characterization.

Key Responsibilities
  • Perform automated and manual high-throughput processing on the Big Hat platform, including DNA preparation, protein expression, and protein characterization.
  • Contribute to the scaling up of Big Hat's platform and production-grade data generation.
  • Support Big Hat's Platform Reagents & Assay Support (PRAS) function by contributing to in-house reagent manufacturing efforts.
  • Execute experiments to optimize the performance efficiency of Big Hat's platform.
  • Keep a detailed record of all experiments using Big Hat's documentation tools, and clearly communicate results and challenges.
  • Collaborate on the creation of laboratory standard operating procedures (SOPs) for sample processing.
  • Collaborate closely with Big Hat team members to identify, design, and implement critical process and operational improvements to production workflows and laboratory systems.
  • Operate automated liquid handlers and analytical instruments to ensure all lab and platform operations run efficiently.
Skills Knowledge and Expertise
  • BS in Biology or Chemistry, with 1+ year(s) of industry experience
  • Experience in process execution, laboratory method development, optimization, and troubleshooting.
  • Hands-on experience with, or interest in, automated liquid handlers (e.g. Hamilton, Open Trons, Tecan, Agilent systems). Experience with LIMS is a nice-to-have.
  • Experience with molecular biology techniques and general lab practices.
  • Efficient time management and ability to work on several projects simultaneously, in a dynamic start-up environment.
  • Strong interpersonal skills and ability to effectively communicate with members of a multidisciplinary team.
  • Excellent record keeping abilities to document experimental work and analytical data.
  • Nice-to-haves include previous experience working with barcoding systems, inventory tracking, and experience with Google Workspace tools (Docs, Sheets, Slides, etc.)
Total Rewards

The salary estimated for this position is $75,000 - $105,000 + bonus + options + benefits. Compensation will vary depending on job-related knowledge, skills, and experience. Actual compensation will be confirmed in writing at the time of the offer.

What Big Hat Offers:

  • Range of health insurance plan options through Anthem and Kaiser (monthly credit if benefit waived)
  • Dental, and vision coverage through Guardian
  • Additional well-being benefits through Nayya, One Medical, Wagmo, Rula, and more
  • 401(k) with company match
  • DTO, two weeks of company-wide shutdown, and 12 company holidays
  • Paid parental leave
About Big Hat Biosciences

Big Hat Biosciences designs safer, more effective biologic therapies for patients using machine learning and synthetic biology.

Big Hat integrates a wet lab for high-speed characterization with machine learning technologies to guide the search for better antibodies. We apply these design capabilities to develop new generations of safer and more effective treatments for patients suffering from today's most challenging diseases. Big Hat is a Series B biotech outside San Francisco with a team-oriented, inclusive, and family-friendly culture. Our broad pipeline of wholly-owned and partnered therapeutic programs span many disparate indications with high unmet need, such as cancer, inflammation, and infectious disease.

Big Hat has raised >$100M from top investors, including Section 32, a16z, and 8VC.

Our Hiring Process

Stage 1:
Applied

Stage 2:
Initial Conversation | Head of Talent

Stage 3:
Initial Conversation | Hiring Manager

Stage 4: 1st Technical Screen

Stage 5: 2nd Technical Screen

Stage 6:
Full Panel Interview

Stage 7:
Offer (Pending References)

Stage 8:
References

Stage 9:
Hired

Not quite right? Register your interest to be notified of any roles that come along that meet your criteria.

Position Requirements
10+ Years work experience
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