Senior Associate Scientist

Title: Clinical - (CW) Sr Research Associate I

Duration: 12+ Months

Senior Research Associate I (Temporary) – Biologics Purification & Characterization

• Client is a global biotechnology company that relentlessly pursues bold science to translate genetic discoveries into transformative medicines for patients with serious genetic diseases. Since our founding in 1997, we have built deep expertise in genetics, molecular biology, and protein sciences to develop first- and best-in-class therapeutics addressing significant unmet medical need.
• About Worldwide Research & Development (WWR) Client's Worldwide Research & Development (WWRD) organization spans early research through post‑market clinical development and includes the scientific teams responsible for discovery, translational research, and development. Our collaborative environment emphasizes scientific rigor, innovation, and meaningful patient impact.

• The Therapeutics Process Development & Characterization (TPDC) group is seeking a highly motivated Temporary Senior Research Associate I to support biologics purification and analytical characterization, with a primary focus on recombinant enzymes and additional exposure to therapeutic proteins, antibodies, and peptide-based modalities.
• This is a primarily laboratory‑based role involving hands‑on purification and characterization of biologics using established chromatography and filtration workflow.
• The successful candidate will independently execute purification experiments, troubleshoot technical challenges, analyze experimental data, and contribute to activities supporting multiple early‑stage and exploratory research programs across projects. The position also supports laboratory operations through routine instrument maintenance.
• The ideal candidate is detail‑oriented, scientifically curious, highly organized, and capable of working independently while collaborating effectively within multidisciplinary project teams.

• Independently perform purification of recombinant enzymes and other therapeutic biologics, including proteins, antibodies, and peptides, using ÄKTA Pure and ÄKTA Avant chromatography system.
• Execute and optimize purification workflows.
• Affinity chromatography: hydrophobic interaction chromatography, desalting and buffer exchange.
• Perform concentration and buffer exchange using tangential‑flow filtration (TFF), ultrafiltration/diafiltration (UF/DF), or centrifugal filtration.
• Evaluate purification performance and recommend process improvements to enhance yield, purity, and recovery.
• Troubleshoot chromatography, filtration, and purification processes with minimal supervision.
• Prepare buffers, reagents, and chromatography columns according to established procedures.
• Perform routine instrument checks, preventative maintenance, and basic troubleshooting of purification equipment.
• Perform analytical assays to assess purity, identity, concentration, and quality of biologics, including SDS‑PAGE, CE‑SDS, DSSEC‑HP, LCRP‑HP, LC‑UV/Vis spectrophotometry.
• Interpret analytical data to support purification process optimization and project decision‑making.
• Analyze experimental results using Graph Pad Prism, JMP, Microsoft Excel, or similar software.
• Communicate experimental findings through technical summaries, presentations, and discussions with cross‑functional project team.
• Support analytical method development, qualification, or technology transfer activities as needed.
• Maintain accurate and complete electronic and/or paper laboratory notebooks.
• Follow established SOPs and document deviations with guidance.
• Communicate results, observations, and progress updates clearly within the team.
• Contribute to a safe, clean, and well‑organized laboratory environment in compliance with safety standards.

• Bachelor's degree in Biochemistry, Biology, Chemical Engineering, or a related scientific discipline with 4–6 years of relevant industry experience.
• or Master's degree in a related scientific discipline with 2–4 years of relevant industry experience.
• Demonstrated experience purifying recombinant enzymes, proteins, antibodies, or peptide…