Principal - Engineer - Automation; Data & Platforms integration
Listed on 2026-09-04
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Engineering
Systems Engineer, Automation & Mechatronics Engineer, Validation Engineer, Data Engineering
At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life‑changing medicines, strengthen how health is understood and managed, and support the communities we serve.
This is hard, urgent, selfless work, but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us.
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader, headquartered in Indianapolis, Indiana. Our 40,000 employees around the world work to discover and bring life‑changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism.
We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.
Lilly is currently constructing an advanced manufacturing facility for production of API molecules located in Houston, TX. This facility is intended to provide APIs for current and future products, including new modalities. This is a unique opportunity to be a part of the site technical team for the startup of a greenfield manufacturing site, and the successful candidate will help to build the Processes, the facility and the culture to enable a successful startup into GMP manufacturing operations.
ResponsibilitiesThe Principal Automation Engineer – Data and Integration Platforms is a mid‑level automation engineering position that requires a deep understanding of process data historians, system integration, Lilly’s computer system validation practices, cGMP standards related to computer systems, and data integrity as they relate to pharmaceutical manufacturing. This role will support the design and delivery of site data historian system, key integration platforms, and the system administration of site servers.
This role will also be integral in the design and delivery of data historian and integration platforms including design, validation plans, system integrator selection and oversight, and developing the site administrative procedures that ensure they remain in a validated state. This role will also support, as a secondary responsibility, related site automation platforms including process automation servers and the DeltaV DCS.
Lilly Houston is part of Lilly’s Drug Substance (Active Pharmaceutical Ingredient) network. During the design and delivery of the project this role will be integrated into the corporate automation team GPACE (Global Process Automation & Control Engineering) and then transition fully to a site‑based process team position. During delivery, this role will collaborate with Lilly Quality, A&E firms, system integrators, Emerson, and corporate and site engineering peers.
Post‑project delivery, this role will support GMP manufacturing operations in the central engineering function supporting site process teams with Data Historian and integration services as well as system administration and platform upgrades. This role will require significant collaboration, creativity and resilience as the site grows to a full scale GMP manufacturing site through start up.
- Champion a strong safety culture, mentor and coach others, and utilize engineering and automation fundamental principles in design and problem solving.
- Become a subject matter expert on Lilly’s Aveva PI Data Historian reference architecture.
- Support the design, delivery, validation, and system management of the site Data Historian and related system integration platforms.
- Lead and direct system integrations and OEM’s on the design and installation of the Aveva PI platforms, data centers, and associated site infrastructure.
- Collaborate with Lilly’s Quality organization, Corporate Engineering, and Global Facilities Delivery to…
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