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Research Engineer II, Fluidic Systems, Research & Early Development

Job in Santa Clara, Santa Clara County, California, 95053, USA
Listing for: F. Hoffmann-La Roche AG
Full Time position
Listed on 2026-09-10
Job specializations:
  • Research/Development
    Research Scientist
Salary/Wage Range or Industry Benchmark: 77400 - 129000 USD Yearly USD 77400.00 129000.00 YEAR
Job Description & How to Apply Below

At Roche you can show up as yourself, embraced for the unique quality you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come.

Join Roche, where every voice matters.

The Position Roche is working to make next-generation sequencing simple and accessible enough for routine use. By accelerating clinical research, streamlining workflows, and expanding assay menus, we are broadening access to genomic data and lowering barriers to adoption. From robust sample isolation and preparation tools to novel sequencing technology and advanced bioinformatics, we are developing differentiated, highly integrated end-to-end solutions for next-generation sequencing, resulting in a sample in, result out workflow.

Our Systems Technology Group, a part of Roche Sequencing Solutions, is focused on creating and advancing technologies to significantly enhance DNA sequencing workflows. We are seeking an enthusiastic, team-oriented Research Engineer II to join the effort.

As a Research Engineer II, you will tackle a variety of tasks and projects that will help us advance our technology and hardware related to our next-generation DNA sequencing systems. Your efforts will cover many aspects related to the chemical engineering and process development for instrument prototypes.

Your Role and Responsibilities
  • Developing orthogonal assays to measure system performance.
  • Operating various and developing processes for various instruments including custom systems such as breadboards and prototypes.
  • Testing, characterizing and optimizing chemical formulations for use in DNA sequencing workflows.
  • Collecting data, documenting observations and helping to analyze, interpret and present results.
  • Utilizing various types of analytical instrumentation to characterize chemicals, chemical mixtures, and surfaces related to prototype instruments.
  • Generating experimental plans, generating reports and communicating results to a broader audience.
  • Collaborating with other scientists and engineers.
Who You Are

(Required) You have a degree in Chemical Engineering, Chemistry, Biochemistry, Molecular Biology, Biomedical Engineering, Bioengineering, or a closely related discipline

You have relevant research and early development experience in the life science industry: 1-5 years for a Bachelor's, 0-4 years for a Master's

Core Technical

Experience:

You have experience with molecular biology workflows, including experience working with DNA and proteins.

You have experience developing assays for fluorescence microscopy and Qubit or other fluorescence spectrometers.

You have experience with common molecular biology tools and process, such as PCR and gel electrophoresis.

You have a solid understanding of chemistry and physics fundamentals, including chemistry and laboratory best practices.

You have a meticulous mindset.

You have a positive, friendly, proactive attitude and a passion for science and technology.

You have a desire to learn and be challenged.

Preferred Qualifications

You have an advanced degree

You have at least 1+ years of industry experience.

You have experience with DNA sequencing workflows.

You have experience with surface chemistry.

You have strong interpersonal and communication skills, with the ability to explain technical concepts to non-experts and thrive in ambiguous environments.

You have excellent organizational skills and the ability to prioritize and manage multiple projects efficiently.

You exhibit a high degree of ingenuity, resourcefulness, and scientific curiosity applied to solving integration challenges and optimizing system performance in an R&D environment.

You have demonstrated a strong desire to learn, be challenged, and proactively challenge the status quo.

This position is based onsite in Santa Clara, CA. This is not a hybrid position. Relocation benefits are not available for this job position.

The expected salary range for this position based on the primary location Santa Clara, CA is $69,400 - $129,000. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.

A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at…

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