Manager, Commercial Accounting

“Mineralys Therapeutics is a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension and related comorbidities such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone. Its initial product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor. Mineralys is headquartered in Radnor, Pennsylvania. For more information, please visit  .

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Mineralys is a fully remote company.

The Manager, Commercial Accounting will be responsible for overseeing accounting activities related to product revenue, gross-to-net reserves, accounts receivable, inventory and cost of goods sold, and other commercial related accounting processes. The role will partner closely with Trade & Distribution, Market Access, CMC, and third-party partners to ensure accurate financial reporting and support commercialization efforts. The Manager will also be responsible for identifying and driving process improvement.

• Manage the monthly close process related to product revenue, gross-to-net reserves, accounts receivable, and related commercial accounting activities.
• Prepare and review journal entries, account reconciliations, and supporting schedules for revenue-related accounts.
• Ensure revenue recognition is recorded in accordance with ASC 606.
• Maintain accurate documentation supporting revenue accounting conclusions and estimates.

• Manage monthly close activities related to inventory and cost of goods sold.
• Oversee inventory accounting activities, including inventory valuation, inventory reserves, inventory reconciliations, and related accounting analyses.
• Review inventory reports and activity received from third-party logistics providers (3PLs) and ensure accurate recording of inventory transactions.
• Monitor inventory movements, adjustments, write-offs, product returns, and related reserve calculations.
• Partner with Trade and Distribution, CMC, and external partners to investigate and resolve inventory discrepancies.
• Support physical inventory count procedures and related reconciliations performed by third-party providers.

• Prepare and maintain gross-to-net reserve calculations, including rebates, chargebacks, returns, prompt pay discounts, distribution service fees, copay assistance programs, and other commercial deductions.
• Collaborate with Market Access, Government Pricing, and Commercial teams to ensure accurate reserve methodologies and assumptions.
• Perform periodic actual-to-estimate analyses and recommend adjustments to reserve methodologies as needed.

• Serve as the primary accounting liaison with third-party logistics providers (3PLs), distributors, and other commercial partners, ensuring timely and accurate transaction processing and reporting.
• Oversee third-party managed order-to-cash activities, including product sales, invoicing, collections, cash applications, deductions, and dispute resolution.
• Ensure timely reconciliation of accounts receivable balances, including oversight of information received from 3PLs and commercial partners.
• Review customer balances, aging reports, collection activities, and related reporting provided by commercial partners and third-party service providers.
• Support the evaluation of customer credit risk, credit limits, and related mitigation strategies in coordination with commercial and finance leadership.

• Partner with Market Access, CMC and Trade & Distribution teams to support commercialization…