Senior Program Manager, Discovery and Translational Sciences

** The Foundation
**** The Team
** Global Health  The Gates Foundation Global Health division harnesses advances in science and technology to save lives in poor countries. We focus on the health problems that have a major impact in developing countries but get too little attention and funding. Where shown tools exist, we support sustainable ways to improve their delivery. Where they don’t, we invest in research and development of new interventions, such as vaccines, drugs, biologics, and diagnostics.

Our work in infectious diseases focuses on strategies to fight and prevent HIV/AIDS, malaria, tuberculosis, neglected tropical diseases, enteric and diarrheal diseases and pneumonia. These strategies are supported by functional teams that focus on Discovery & Translational Sciences, Vaccine Development, Integrated Development.
The Discovery Team   The mission of Discovery & Translational Sciences (D&TS) is to catalyze innovation for the discovery and translation of transformative Global Health (GH) solutions. The primary role of D&TS is to support the foundation to achieve its ambitious equity goals as articulated in the objectives of the program strategies in GH and the Women’s Health Innovations program in Gender Equality (GE).

For this, we exploit a unique advantage of the foundation in general and D&TS in particular: the ability to invest in high-risk initiatives with potential for truly disruptive change. We channel resources into creating more practical (affordable, scalable, deliverable) versions of existing tools, develop transformative new tools where none exist, and speed the translation of scientific discovery into implementable solutions, seeking better ways to evaluate and refine potential interventions before they enter costly and time-consuming late stage clinical trials.

Key functions in support of this R&D mission include identifying and filling gaps in scientific knowledge, creating or implementing new technology platforms that can accelerate research in support of our goals, investing in potentially transformative ideas, continuous surveying of an ever-changing scientific and technological innovation space, and the fostering of an effective ecosystem of global health innovation, funding, and partnership to advance the foundation’s mission.

Our intervention areas of focus include vaccines, biologics, drugs, and microbiome, as well as reproductive and sexual health.
Our work is organized into the following domains:  
• Two tool-focused domains (Drugs; Vaccines & Biologics) and one topic-focused domain (Reproductive Health Technologies) that focus on our core pipeline of interventional product candidates.  
• Three functional domains that support and accelerate the above work:
Global Partnerships & Grand Challenges, which focuses on global health innovation sourcing and ecosystem support, particularly for priority low- and middle-income countries;
Translational Sciences, which works to accelerate translation of products and technologies to maximize their potential impact; the Global Health Discovery Collaboratory, which provides foundation grantees with access to best-in-class technologies and platforms and fosters a collaborative network of centers of excellence in technological innovation, technology platforms, and grantees.
The Vaccines and Biologics (VxBx) domain has a large and growing portfolio of investments in innovative approaches and platforms aimed at the prevention of infectious diseases whose burdens are a major source and manifestation of inequity. As a functional team, we engage deeply and in a highly matrixed fashion with all our program strategy partners (e.g., Malaria, HIV, TB, Pneumonia and Pandemic Preparedness, Enteric and Diarrheal Diseases, Neglected Tropical Diseases, and Women’s Health Innovations) and other functional teams (e.g., Vaccine Development).

Outside the foundation, we work closely with diverse external not-for-profit and for-profit partners including academia, biotech, pharma, government agencies, and other key funders.
The Global Health Discovery Collaboratory (https://(Use the "Apply for this Job" box below).) domain brings the leading edge of…