Clinical Research Associate

About Us

Eupraxia is a clinical-stage biotechnology company focused on developing locally delivered, extended-release products that have the potential to address therapeutic areas with high unmet medical need. Diffu Sphere™, a proprietary, polymer-based micro-sphere technology, is designed to facilitate targeted drug delivery of both existing and novel drugs. The technology supports an extended duration of effect and delivers drugs in a hyper‑localized fashion, targeting only the tissues that physicians want to treat.

Precision targeting and a stable, flat delivery of the active ingredient may achieve fewer adverse events compared with traditional drug delivery methods, which exhibit peaks and troughs. Eupraxia’s Diffu Sphere™ technology platform has the potential to augment and transform existing FDA‑approved drugs to improve safety, tolerability, efficacy, and duration of effect. Potential therapeutic uses extend beyond pain and inflammatory gastrointestinal disease—current development areas—and may be applicable in oncology, infectious disease, and other critical disease areas.

Eupraxia’s EP‑104GI is in a Phase 1b/2 trial for eosinophilic esophagitis (EoE), while EP‑104

IAR, a Phase 2b trial for knee osteoarthritis pain, met its primary endpoint and three of four secondary endpoints. The company is developing a pipeline of later- and earlier-stage long‑acting formulations for inflammatory joint indications and oncology.

As our Clinical Research Associate (CRA) you will be primarily responsible for the operational management and oversight of Eupraxia clinical study monitoring.

Travel requirement:
Must be willing to travel domestically and internationally (approximately 20–25%) as needed.

Reports to:

SVP of Clinical Operations

• Assist the Clinical Trial Manager in ensuring trials are initiated efficiently, completed on time, within budget, and conducted in compliance with SOPs, regulations, and ICH/GCP guidelines.
• Assist the Clinical Trial Manager in managing CRO partners and other vendors.
• Work closely with and provide training to CRO staff, study site staff, and field‑based CRAs.
• Oversee, conduct, and/or co‑monitor site qualification, study initiation, interim monitoring, and close‑out visits, and complete associated reports.
• Develop and/or assist in developing trial materials (e.g., protocol, informed consent forms, case report forms (CRF), CRF completion guidelines, monitoring guidelines, site initiation visit materials, site tools and worksheets, product administration guidelines).
• Review monitoring reports and monitoring visit letters written by CRO CRAs.
• Drive CRO and trial sites with study startup activities, including IRB/IEC submissions and ensuring collection and review of required essential documents.
• Create, monitor, and share key performance metrics with study teams.
• Review completed CRFs and data listings for accuracy, oversee data discrepancy management, and perform associated training/retraining of site staff and CRAs as needed.
• Develop strong and effective working relationships within Clinical Operations and other functional departments and CROs.

• BS/BA in life sciences or related discipline.
• 5+ years of pharma/biopharma industry experience, preferably in a sponsor‑side role.
• 1+ year of active, independent, on‑site monitoring experience for all types of visits.
• Strong working knowledge of FDA and ICH/GCP regulations and guidelines.
• Thorough knowledge of clinical monitoring procedures.
• Strong interpersonal, communication (written and verbal), and organizational skills.
• Excellent analytical and assessment skills, judgment, and problem‑solving skills.

Salary Range: $115,000 – $145,000 annually depending on education and relevant experience.