Research Associate In Vivo Electrophysiology & Behavior

The mission of the Allen Institute is to understand the principles that govern life and to advance health. Our creative and multi-dimensional teams focus on answering some of the biggest questions in bioscience. We accelerate foundational research, catalyze bold ideas, develop tools and models, and openly share our science to make a broad, transformational impact on the world.

The mission of the Allen Institute for Neural Dynamics is focused on fundamental discoveries in systems neuroscience. We are interested in how the brain builds our understanding of the complex world to guide the flexible behaviors that address our biological needs. The answers will be in terms of defined neuron types and circuits interacting across the whole brain and body. We will develop next-generation methods and theories and employ a team-based approach to discovery in neuroscience.

Knowledge, data, models, and tools will be widely shared to support the development of therapies for brain disorders.

We are seeking a Research Associate to contribute to a set of projects to record the activity of thousands of neurons distributed across many brain regions in parallel. The ideal candidate will be team-oriented, have knowledge in neuroscience and behavior, and display a strong interest in studying brain-wide circuits during behavior. This position will leverage state-of-the-art electrophysiological methods, such as Neuropixels probes, as well as molecular and transgenic resources.

The goal is to record simultaneously from many anatomically connected regions while mice are engaged in a variety of cognitive tasks. The Research Associate will work alongside a diverse team of Scientists, Technicians, Engineers, and Investigators, and so collaboration and communication skills are key.

At the Allen Institute, we believe that science is for everyone – and should be open to everyone. We are dedicated to combating biases and reducing barriers to STEM careers more broadly.

We also believe that science is better when it includes different perspectives and voices. We strive to make the Allen Institute a place where everyone feels like they belong and are empowered to do their best work in a supportive environment.

We are an equal-opportunity employer and strongly encourage people from all backgrounds to apply for our open positions.

• Collect in vivo electrophysiological, optogenetics, and/or optical physiological data from mouse cortex using cutting-edge recording systems
• Train mice to perform various foraging behavioral tasks
• Participate in lab maintenance and weekly tasks
• Carry out analyses to assess overall data quality and use this information to update and refine experimental protocols
• Use histological techniques to identify probe recording location

• Bachelor’s degree in neuroscience or a related field

• 2 years of experience in a research lab
• Experience working with mice greatly preferred
• Practical experience in in vivo electrophysiology and/or mouse behavior
• Strong scientific communication skills (written and oral)
• Ability to work in a team-based environment
• Experience with rodent surgeries
• Laboratory environment - possible chemical, biological, or other hazardous substances exposure Possible exposure to Bio Safety Level 2 organisms, such as recombinant viruses This may include wearing personnel protective equipment (PPE)

• Exposure to and handling of laboratory animals required
• Pre and post-operative care for mice
• Administration of compounds to mice (iv, ip, sc, po, im, ro, icv)
• Perform health assessments of mice
• Perform euthanasia and tissue collections

• Fine motor movements in fingers/hands to operate computers and other office equipment; repetitive motion with lab equipment
• Stooping, bending, crouching
• Reaching, or climbing ladders

• This role is currently working onsite and is expected to work onsite for the majority of working hours. The primary work location for this role is 615 Westlake Ave N., with flexibility to work remotely on a limited basis.

• All…