Scientist II, Process Development

This position is on-site in Seattle, WA.

Join Lumen Bioscience as a Scientist II, Process Development to lead the development, optimization, and qualification of scale-down models for upstream and downstream processes supporting complex biologics in an innovative early-stage manufacturing environment. In this role, you will apply process modeling DoE strategies to maximize product potency and productivity, design and execute complex experimental studies using sound statistical methodologies, and lead technology transfer efforts across Lumen's portfolio.

We are looking for a scientist with deep expertise, who thrives on independently driving complex technical initiatives and excels in a highly cross-functional environment. You will collaborate closely with Manufacturing and R&D teams to ensure alignment and successful program execution, clearly communicate scientific strategy, risks, data interpretations, and recommendations to project teams, leadership, and internal and external partners. You will author technical reports, protocols, and presentations, execute assigned milestones on time while upholding high scientific standards, and have the opportunity to supervise and mentor junior team members.

• Lead the development, optimization, troubleshooting, and qualification of scale-down models for upstream and downstream processes for complex biologics.
• Design, execute, and analyze complex experimental studies using sound statistical and DoE methodologies.
• Lead technology transfer efforts.
• Ensure timely execution of assigned milestones while maintaining high scientific standards.
• Collaborate cross‑functionally with Manufacturing and Research & Development teams to ensure alignment and successful program execution.
• Clearly communicate scientific strategy, risks, data interpretations, and recommendations to project teams, leadership, and internal/external partners.
• Maintain thorough and timely documentation in electronic laboratory notebooks and company systems.
• Author technical reports, protocols, and presentations for internal and external audiences.

• Education and Experience
  • PhD or equivalent experience in phycology, plant biology, molecular biology, biochemistry, microbiology, or chemistry.
  • Minimum of five years’ experience with biochemistry, microbiology, or molecular biology.
  • Demonstrated expertise with upstream or downstream process modeling for biologics.
  • Experience with multi‑factor Design‑of‑Experiments (DOE), data analysis, and troubleshooting skills.
  • Experience culturing microorganisms at research, pilot, and commercial scale (preferred).
  • Hands‑on experience or willingness to learn biochemical and immunoassays (ELISA, MSD, SDS‑PAGE, western blot, etc.), spectroscopic or fluorescence‑based techniques, or quantitative PCR protocols.
• Skills and Attributes
  • Excellent organizational skills with meticulous attention to detail.
  • Ability to manage multiple priorities and deliver high-quality results on time.
  • Resourceful with proven ability to lead, manage, and leverage internal and external resources to plan and resolve issues.
  • Strong interpersonal and collaborative skills to promote team success.
  • Effective written and verbal communication skills, including the ability to explain complex technical concepts clearly.
  • Demonstrated integrity, sound scientific judgement, and professional ethics.
  • Ability to work both independently and in a highly collaborative team environment.

• Ability to work on‑site in Seattle, WA.
• Ability to sit or stand for extended periods of time (2 or more hours).
• Occasional lifting or carrying up to 23 kg.
• Perform delicate manual laboratory procedures.

• Stock bonus
• Health, Dental, and Vision premiums fully covered by Lumen.
• 401k match up to 4%.
• Industry‑leading PTO policy, paid refresh days, and paid year‑end holiday office closure.
• Monthly wellness program to support your health and well‑being.
• Free onsite parking or public transportation subsidies.
• Comprehensive parental leave policies.
• Life insurance, short‑ and long‑term disability, and employee assistance programs.

At Lumen Bioscience, we foster a workplace built on collaboration, innovation, and professional growth. This role offers a significant opportunity to contribute directly to cutting‑edge biotechnology and the advancement of global health solutions.

We do not discriminate on the basis of any protected group status under any applicable law. (Equal Employment Opportunity Statement)

Compensation Range: $115,000 - $125,000 USD