Research Scientist​/Engr

Position: Research Scientist/Engr 4
## Research Scientist/Engr 4

Apply locations:
Seattle, WAtime type:
Full time posted on:
Posted 13 Days Agojob requisition :
REQ
- ** Job Description
**** Field of research:
** Single particle cryo-electron microscopy and X-ray crystallization of viral glycoproteins, immunogen design, virology, biochemistry and biophysics.
** Purpose of the Research Project(s):
** The goal of our research is to develop vaccines and therapeutics targeting human pathogens.
*
* Duties and Responsibilities:

** 20% Structure-based and machine-learning immunogen design for protein subunit and mRNA vaccines based on viral surface glycoproteins (construct design, recombinant expression in mammalian cells, purification, and stability assays),20% Characterize protein antigenicity (binding assays using ELISAs, SPR and biolayer interferometry to evaluate binding kinetics and affinity of antibodies or designed proteins),15% Perform structural studies (high-throughput cryo-electron microscopy of subunit vaccines as well as of complexes between viral glycoproteins and monoclonal and polyclonal antibodies as well as X-ray crystallography), 10% Design and execution of virology assays,10% Analysis of the data to help determining the research strategy,10% Lead projects and/or major project tasks,10% Interactions with collaborators within our network and writing of manuscripts for publication 5% Provide guidance and direction to project staff, students and postdocs
** Requirements:
** Master's Degree in Biochemistry or related field and four years 4 years of experience in related field like:
Cryo-electron microscopy, virology assays (pseudotyped virus generation, cellular entry and neutralization assays), protein expression in mammalian cells and purification

Equivalent education and/or experience may substitute for minimum qualifications except when there are legal requirements, such as a license, certification, and/or registration.
** Desire:
** Expertise in protein and vaccine design, experience in high throughput automation using Beckman Biomek.
** Compensation, Benefits and Position Details
**** Pay Range Minimum:**$99,444.00 annual
** Pay Range Maximum:**$ annual
** Other Compensation:**
- ** Benefits:
** For information about benefits for this position, visit https://(Use the "Apply for this Job" box below)./
** Shift:
** First Shift (United States of America)
** Temporary or Regular?
** This is a regular position
** FTE (Full-Time Equivalent):
** 100.00%
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