Senior Program Officer, TB​/HIV Diagnostics Research & Development

TB Diagnostics R&D Strategy Lead

The Foundation is the largest nonprofit fighting poverty, disease, and inequity around the world. Founded on a simple premise: people everywhere, regardless of identity or circumstances, should have the chance to live healthy, productive lives. We believe our employees should reflect the rich diversity of the global populations we aim to serve. We provide an exceptional benefits package to employees and their families which include comprehensive medical, dental, and vision coverage with no premiums, generous paid time off, paid family leave, foundation-paid retirement contribution, regional holidays, and opportunities to engage in several employee communities.

As a workplace, we're committed to creating an environment for you to thrive both personally and professionally.

Our Global Health division harnesses advances in science and technology to save lives in developing countries. We focus on the health problems that have a major impact in developing countries but get too little attention and funding. Where tools exist, we support sustainable ways to improve their delivery. Where they don't, we invest in research and development of new interventions, such as vaccines, drugs, and diagnostics.

Our work in infectious diseases focuses on strategies to fight and prevent HIV/AIDS, malaria, tuberculosis (TB), neglected tropical diseases, enteric and diarrheal diseases, pneumonia and maternal, newborn and child health.

You will be primarily responsible for refining, informing and advancing the TB Diagnostics R&D strategy through the shaping and management of a portfolio of high-impact investments aimed at accelerating the development, and validation of novel TB diagnostics and diagnostic devices for use in low- and middle-income countries (LMICs). You will work in close partnership with the EDGE (Enterics, Diagnostics, Genomics & Surveillance) and TB Delivery teams to guide scientific, technical, and partnership aspects of the diagnostics development pipeline and ensure alignment with the foundation's TB diagnostics introduction goals.

You will also collaborate with the HIV team to refine the HIV Diagnostics strategy and define potential high value HIV diagnostics investments designed to advance the foundation's HIV product introduction priorities. Together the role includes contributing to strategy formulation, managing complex grants and contracts, engaging with a diverse set of partners, and staying at the forefront of innovation and trends in diagnostics technologies.

You will report to the Deputy Director of TB Drugs & Diagnostics R&D.

What You'll Do

• Lead and manage a strategic diagnostics R&D investment portfolio, applying scientific, technical, and business expertise to identify, assess, fund, and oversee grants and contracts across discovery, technology validation, clinical evaluation, and implementation readiness.
• Provide strategic and technical leadership in diagnostics and device product development, including risk-based decision-making, iterative milestone planning, and expert guidance to product developers, PDPs, academic groups, and implementing partners.
• Drive the creation and refinement of target product profiles (TPPs), use cases, and value propositions for TB/HIV diagnostics across diverse settings and populations, ensuring alignment with broader TB and HIV treatment and prevention strategies.
• Shape and implement program strategy by partnering with team leadership and contributing to the cross-functional TB/HIV Diagnostics R&D Initiative, including goal setting, investment planning, and execution.
• Review and recommend funding opportunities, including evaluation of letters of inquiry and proposals, and prepare clear, concise analyses and funding recommendations for internal stakeholders.
• Monitor and evaluate investment performance, conducting site visits, convening stakeholders, supporting grantees, and ensuring progress toward defined milestones and outcomes.
• Cultivate and manage partnerships across the TB/HIV ecosystem, including PDPs, diagnostics developers, pharmaceutical companies, academic institutions, global experts, and implementing agencies; proactively identify and establish new collaborations to accelerate innovation.
• Stay current with scientific, technological, and market trends relevant to diagnostics development—especially for low- and middle-income country settings—and surface innovative approaches to accelerate cost-effective, geographically diverse product development.
• Collaborate closely with internal teams (e.g., TB/HIV R&D, TB/HIV Delivery, EDGE) to ensure diagnostic innovations integrate effectively with treatment and prevention R&D and delivery strategies.
• Manage portfolio information and decision processes, documenting key activities, contributing to business processes and performance measurement tools, and preparing materials for communication with foundation leadership.
• Represent the foundation externally, engaging in global development networks and…