Senior Associate Scientist, Gene Delivery and Editing Process Development

Position Summary

• Support process development, production, and characterization of early and late-stage viral vectors (lentiviral vectors and/or adeno-associated viruses) for engineered T cell manufacturing.
• Provide technical subject matter expertise for internal/external collaborators across tech transfer, process characterization, and pre-clinical/clinical process lifecycle management.

• Perform hands‑on upstream viral vector development/optimization (mammalian cell culture, stirred tank bioreactors, transient transfection); downstream experience (clarification, AEX chromatography, Tangential Flow Filtration) is a bonus.
• Support process and technology development for viral vector manufacturing platforms.
• Support late-phase development, including process characterization.
• Design, plan, execute, and analyze lab experiments using statistical design of experiment (DOE) principles.
• Maintain documentation in an electronic lab notebook.
• Summarize/present data and communicate progress.
• Author technical documents (protocols and internal development reports).
• Follow lab safety rules and practices.

• B.S. with 5+ years or M.S. with 2+ years of hands‑on upstream experience (downstream is a plus).
• Ability to use DOE approaches; interpret results using statistical software (e.g., JMP).
• Independently motivated; multitask, problem‑solve, train others on lab operations, and coordinate within a team.
• Strong interest in biological mechanisms of cell/gene therapy products and impact on patients.
• Clear oral presentation and technical writing skills.

• Health coverage (medical, pharmacy, dental, vision); wellbeing support; 401(k); disability and life insurance; other listed financial protections.
• Paid time off (flexible/unlimited for US exempt employees; or 160 hours annual paid vacation for certain Phoenix/Puerto Rico/Rayzebio employees), plus national holidays.