Analytical Methods and Instrumentation Scientist
Listed on 2026-09-22
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Research/Development
Research Scientist, Biotech Research, Biomedical Science, Pharmaceutical Science/ Research
About this Opportunity
The Institute for Protein Design (IPD) at the University of Washington is a world-leading research center focused on creating new proteins that solve challenges in medicine, technology, and sustainability. Founded by Nobel laureate David Baker, the IPD fosters a collaborative, interdisciplinary environment, bringing together expertise in computational design, biochemistry, genome sciences, and structural biology. Current projects include the development of novel therapeutics, vaccines, enzymes, and protein-based nanomaterials.
Learn more .edu.
The Institute for Protein Design (IPD) at the University of Washington is a world-leading research center focused on creating new proteins that solve challenges in medicine, technology, and sustainability. Founded by Nobel laureate David Baker, the IPD fosters a collaborative, interdisciplinary environment, bringing together expertise in computational design, biochemistry, genome sciences, and structural biology. Current projects include the development of novel therapeutics, vaccines, enzymes, and protein-based nanomaterials.
Learn more .edu.
The Analytical Methods and Instrumentation Scientist (Research Scientist/Engineer
3) will play a critical role in strengthening IPD’s analytical and purification capabilities. By developing reliable, general‑use methods for small‑molecule analysis, enzyme characterization, and chromatography workflows, this position directly supports a wide range of protein design and enzyme engineering projects. In addition to method development and data analysis, the RS3 provides extensive training for graduate students, postdocs, and other researchers across core instrumentation such as FPLC, HPLC, LC‑MS, and SPR systems.
This work ensures that IPD scientists can generate high‑quality and reproducible data and builds long‑term technical capacity essential to IPD’s mission to design proteins that address global challenges.
- Train and mentor graduate students, postdoctoral fellows, and other research staff in FPLC (AKTA), U/HPLC (Agilent), LC‑MS (Agilent), SPR (Cytiva), and related analytical techniques.
- Develop and maintain standard operating procedures for instrument operation, preventative maintenance, method execution, troubleshooting, and data analysis.
- Provide ongoing scientific and technical guidance to help trainees build long‑term competency in analytical workflows and instrument care.
- Develop, optimize, and validate analytical and purification methods for small molecule analysis, enzyme characterization, and chromatography workflows using FPLC (AKTA), U/HPLC (Agilent), LC‑MS (Agilent), SPR (Cytiva), and related analytical systems.
- Perform data analysis to improve sensitivity, reproducibility, and throughput across IPD analytical pipelines.
- Create general‑use protocols and reference datasets that support consistent and reproducible use of core instrumentation.
- Collaborate with researchers to refine methods that support small molecule, protein and enzyme design and contribute to the interpretation of analytical results.
- Manage and maintain IPD instrumentation including FPLC (AKTA), U/HPLC (Agilent), LC‑MS (Agilent), SPR (Cytiva), and related analytical systems and other core analytical equipment.
- Coordinate routine maintenance schedules and ensure instruments remain reliable and ready for high‑throughput use.
- Monitor instrument performance, identify emerging issues, and implement improvements that support IPD research needs.
- Support IPD researchers by ensuring equitable access to…
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