Researcher II

Cognizance Technologies, LLC | Full time

Silver Spring, United States | Posted on 06/23/2026

Development of Glyco-engineered CHO cells for improving protein drug quality and safety. This project will fund a contracted professional with an MS or PhD in biochemistry, glycobiology, molecular biology, chemistry, pharmaceutics, or related field. For a candidate possessing an MS, at least two years of relevant experience is required in biopharmaceutical manufacturing, quality analytics, biotechnology research and development or other relevant areas.

• Establish and fully characterize genetically modified (engineered) cell lines.
• Purify the therapeutic proteins produced by engineered CHO cell lines.
• Analyze the glycans of therapeutic proteins, endogenous glycoproteins, and other glycoconjugates with mass spectrometry (MS), such as MALDI-TOF, LC-MS, and Ion‑mobility spectrometry–MS (IMS-MS or IMS), (U)
  HPLC and other state‑of‑the‑art technologies.
• Establish new analytical methods to release and analyze O‑glycans from glycoproteins.
• Establish new analytical methods and procedures for testing the quality of protein drugs.
• Summarize and prepare data reports using Microsoft Word or Power Point.
• Have weekly progress meetings to update the PI and report any pitfalls or shortcomings.
• Write manuscripts and/or technique reports for publications or white papers on the project.

• MS or PhD in biochemistry, glycobiology, molecular biology, chemistry, pharmaceutics, or related field.
• At least two years of relevant experience in biopharmaceutical manufacturing, quality analytics, biotechnology research and development, or other relevant areas.

• PPO/HMO Health Plan (includes medical, dental, and vision)