Senior Computational Engineer; CLIMB

Senior Computational Engineer (CLIMB) – United Therapeutics Corporation – Silver Spring, MD

The Senior Computational Engineer (CLIMB) position at United Therapeutics Corporation focuses on advanced computational research to simulate in silico continuum fluid mechanics, lung tissue mechanics, and blood-tissue interactions pertinent to cardiovascular diseases such as pulmonary hypertension and idiopathic pulmonary fibrosis. This role integrates imaging and pathology data to enhance anatomical accuracy, estimates model parameters, validates model output, and applies numerical methods for partial differential equations.

• Apply advanced engineering and applied mathematics concepts to develop and implement processes for simulating lung ventilation and perfusion, lung tissue mechanics, and blood-tissue interactions in the context of cardiovascular diseases.
• Apply continuum modeling techniques to simulate lung tissue mechanics and related air and blood flow, focusing on integrating imaging and pathology data to enhance anatomical accuracy.
• Estimate model parameters and validate model output through comparison to physiological data.
• Apply knowledge of numerical methods relevant to modeling and simulation of partial differential equations.
• Collaborate with other computational engineers and biologists to integrate models of fluid and tissue mechanics into large multiscale models spanning organ to molecular levels.
• Support computational laboratory efforts to use cloud-based high-performance computing for large-scale biological system simulations.
• Communicate results effectively through interactive visualizations, presentations at internal and external meetings, and peer-reviewed publications.

• PhD in an engineering or applied mathematics field with 12 months full‑time equivalent experience in a Computational Research position focused on fluid flow and tissue mechanics (postgraduate or higher degree program experience considered qualifying).
• MSc in an engineering or applied mathematics field with 36 months full‑time equivalent experience in such a position (postgraduate experience considered qualifying).
• BSc in an engineering or applied mathematics field with five years full‑time equivalent experience in such a position (postgraduate experience considered qualifying).
• 12 months full‑time equivalent experience performing all aspects of the computational modeling workflow for fluid or tissue mechanics, including domain creation or reconstruction, mesh generation, solver handling, and data post-processing and visualization.
• Proficiency in at least one of the following industry‑standard scientific programming languages: C++, Python, R, Julia, or MATLAB.
• Experience modeling and simulating partial differential equations using numerical libraries or frameworks such as Sci Py, SUNDIALS, MATLAB, or Differential Equations.jl.
• Experience modeling physiology employing multi‑scale simulation techniques and reduced‑order modeling approaches.

Offered wage: $134,930 – $140,000 per year with standard corporate benefits.

• Medical, dental, vision, and prescription coverage
• Employee wellness resources
• 401(k) and ESPP savings plans
• Paid time off and paid parental leave benefits
• Disability benefits
• Additional benefits available via United Therapeutics' comprehensive benefits suite

United Therapeutics Corporation is an equal opportunity employer, including veterans and individuals with disabilities.