Senior​/Principal Bioinformatician - Transcriptomics

An exciting hybrid working opportunity has arisen for an experienced Bioinformatician to join a high-impact team supporting clinical-stage assets. Working at the interface of biology and data, you’ll play a key role in unlocking insights from complex patient-level omics datasets to better understand disease biology, treatment effects and safety signals. This is a collaborative environment where your work will directly inform critical scientific and clinical decisions.

In this role you will:

• Analyse and interpret large-scale omics datasets (with a strong focus on bulk and single-cell RNAseq)
• Develop and refine bioinformatics pipelines and analytical approaches
• Generate meaningful biological insights to support clinical programmes
• Work with cross-functional stakeholders to communicate findings clearly and effectively
• Ensure robust documentation, reproducibility and best practice coding standards
• Contribute to scientific reports, presentations and publications

You will bring:

• MSc/PhD with significant postdoctoral or industry experience (5+ years)
• Deep expertise analysing large bulk and single-cell RNAseq datasets from complex (ideally clinical) studies
• Strong programming skills (R essential; others beneficial)
• Experience of operating in a HPC Unix environment, cloud-based computational and/or pipelining platforms, and containerization technologies (e.g., Docker
• Confident developing and applying methods for functional interpretation of omics data
• Proven ability to build, adapt and understand bioinformatics pipelines, deriving relevant biological insights (not just run them)
• A clear, confident communicator, able to translate complex data to a range of shareholders
• Ability to document code and follow coding best practices
• A detail-oriented, scientifically rigorous mindset

If you’re looking for a role where your expertise will genuinely shape scientific understanding and influence decision-making, we’d love to hear from you.

The job holder is expected to work from the company's HQ is Slough approx. 40% of the working week.

This role is offered on an initial 12 month contract with realistic potential for extension.

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