Senior Finance Associate, Innovation

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Mass General Brigham Incorporated Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

Job Summary Mass General Brigham Ventures is an early-stage venture capital firm founded in 2008 to translate breakthrough science into impactful therapies and technologies. As the venture arm of Mass General Brigham, one of the world’s leading medical research institutions, we invest in bold, transformative innovations to improve outcomes and advance patient care worldwide.

The Role This is a unique opportunity to join a highly collaborative and mission-driven team at the intersection of life sciences, finance, and innovation. As a Senior Finance Associate, you’ll play a key role in supporting the financial and operational success of our portfolio of cutting-edge life science investments. You’ll partner with colleagues across the finance, investment, and investor relations functions—as well as with external administrators, accountants, and banking partners—to ensure smooth execution and reporting for all venture fund activities.

Reporting Structure The Senior Finance Associate reports to the Senior Director of Finance and works closely with other members of the venture capital and innovation teams.

Key responsibilities:

Manage cash flow spreadsheets to monitor portfolio company investments, returns, and performance metrics.

Collaborate with external financial professionals such as the fund administrator, independent accountants, banks, and brokers to ensure accurate, timely execution of fund operations.

Support the preparation of financial reports and presentations for the Investment Committee, Limited Partners (LPs), and internal governing boards.

Partner with internal treasury operations to align capital flow projections and portfolio performance tracking.

Oversee the annual audit and tax filing processes, ensuring all submissions and documentation are accurate and on schedule.

Create investor-facing materials, presentations, and financial summaries to support fundraising and LP communications.

Plan and coordinate capital calls and distributions.

Prepare and initiate wire transfers for investments.

Uphold strong internal controls and help safeguard the firm’s financial assets through adherence to best accounting practices.

Qualifications Bachelor’s or higher degree in Accounting or Finance required4-6 years of relevant experience in venture capital, private equity, public accounting, or fund administration required.

Advanced Excel expertise, including proficiency with complex formulas, data modeling, and financial analysis tools; true Excel power user.

Strong understanding of venture capital fund structures, including capital call and distribution processes, waterfall modeling, and carried interest calculations.

Proven ability to build, maintain, and interpret cash flow models and valuation analyses.

Solid grasp of GAAP accounting principles and fund financial reporting requirements.

Exceptional analytical skills and attention to detail; proactive, resourceful, and able to work independently in a fast-paced environment.

Clear, professional communication skills—both written and verbal—with the ability to distill complex data into concise insights.

Creative presentation design skills with the ability to develop polished, investor-ready PowerPoint presentations and other visual financial materials.

Interest or experience in the life sciences sector is preferred—but a passion for innovation and precise financial execution is essential.

Additional Job Details (if applicable)
Remote Type Hybrid Work  Location
399 Revolution Drive Scheduled Weekly Hours
40

Employee Type Regular Work  Shift Day (United States of America)
Pay Range $79,560.00 - $/Annual Grade7

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