Senior Director, Protein Analytics & Biophysics

The Role

Generate:

Biomedicines is seeking a scientifically bold, highly collaborative Senior Director to lead Protein Analytics & Biophysics within our Therapeutics division. This leader will set the vision for how Generate measures the biophysical, biochemical, and interaction properties of protein therapeutics across the design-build-test-learn cycle, from conventional analytical characterization through next-generation pooled, miniaturized, and nanoscale measurement platforms.

We are looking for a field‑leading biophysicist and platform builder who has not only operated best‑in‑class analytical and protein interaction workflows, but has also invented, scaled, or industrialized new ways to measure protein therapeutic attributes at orders‑of‑magnitude higher throughput and lower sample consumption. The right person will be energized by the challenge of connecting micro‑ and nanoscale assay innovation with Generate's AI/ML‑enabled protein design engine.

This role will own the continued excellence of conventional protein analytics, develop ability, and protein‑protein interaction technologies while building the next generation of at‑scale experimental systems. The ideal candidate brings deep technical breadth, a quantitative mindset, and a clear point of view on how pooled assays, DNA/barcode‑enabled readouts, synthetic biology, automation, microfluidics, advanced detection, and computational modeling can transform how protein therapeutics are evaluated.

Success in this role will require enterprise leadership: developing leaders and senior scientists, building an inclusive and high‑accountability culture, partnering deeply across Protein Sciences, Prototyping, Technology, Data Sciences, Machine Learning, Biology, and CMC/Tech Ops, and translating an ambitious scientific vision into robust capabilities that improve decision quality, speed, and scale.

• Set and drive the multi‑year scientific and organizational vision for Protein Analytics & Biophysics, aligning functional strategy with Generate's platform, portfolio, and company priorities.
• Define the next generation of biophysical, biochemical, develop ability, and protein‑protein interaction measurement capabilities for protein therapeutics, with a particular focus on miniaturized, pooled, high‑throughput, and nanoscale approaches.
• Lead the continued evolution of conventional analytical and interaction workflows, including HPLC/UPLC, LC/MS, electrophoretic, thermal stability, light scattering, plate‑based, and biosensor‑based platforms, ensuring rigor, reproducibility, and decision relevance.
• Build a strategy that connects conventional analytical and biosensor technologies with emerging pooled or massively multiplexed approaches, enabling Generate to measure protein attributes at scales that match the output of generative design.
• Partner with Prototyping, Technology, Automation, Data Sciences, Machine Learning, Protein Sciences, Biology, and CMC/Tech Ops to design, operationalize, validate, and scale new assay concepts into production‑quality capabilities.
• Identify, evaluate, and implement external and internal technologies that can unlock smaller sample volumes, richer attribute profiles, higher throughput, improved sensitivity, or new classes of protein interaction and develop ability data.
• Establish data standards, quality expectations, assay controls, and analytical frameworks that allow high‑throughput measurements to be used confidently for model training, candidate triage, and program decision‑making.
• Ensure the function generates high‑quality, decision‑enabling data across Discovery, Candidate Selection, and early Development, including develop ability, stability, specificity, affinity, kinetics, and manufacturability‑relevant attributes.
• Drive operational excellence across the function, including prioritization, resource planning, milestone delivery, metrics, continuous improvement, and clear communication of trade‑offs.
• Represent the function with executive stakeholders and external partners, translating complex scientific strategy into clear, compelling, and actionable plans.

• Lead as a strong…