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Distinguished Scientist, Group Head Biochemistry

Job in Somerville, Middlesex County, Massachusetts, 02145, USA
Listing for: Sanofi
Full Time position
Listed on 2026-06-29
Job specializations:
  • Research/Development
    Research Scientist
  • Healthcare
Salary/Wage Range or Industry Benchmark: 100000 - 150000 USD Yearly USD 100000.00 150000.00 YEAR
Job Description & How to Apply Below

Key Responsibilities

  • Provide strategic direction and scientific oversight for biochemistry activities supporting multiple drug discovery programs across diverse therapeutic areas
  • Serve as the primary biochemistry expert and thought leader, guiding project teams on assay design, target characterization, and mechanism of action studies
  • Drive innovation in biochemical assay technologies and methodologies to enhance drug discovery capabilities
  • Establish and maintain scientific standards and best practices for biochemistry within In Vitro Biology
  • Represent biochemistry expertise in cross‑functional project teams and governance committees
  • Use AI/ML and robotics to accelerate drug discovery cycle times
Team Leadership & Development
  • Lead, mentor, and develop a team of biochemists, fostering a culture of scientific excellence and collaboration
  • Recruit, retain, and develop top scientific talent to build a world‑class biochemistry organization
  • Conduct performance management, including goal setting, feedback, and career development for direct reports
  • Create an inclusive environment that encourages innovation, continuous learning, and professional growth
  • Promote Sanofi's values of Aim Higher, Act for Patients, Be Bold, and Lead Together within the team
Drug Discovery Execution
  • Oversee the design, development, and execution of biochemical assays for target validation, hit identification, and lead optimization
  • Ensure timely delivery of high‑quality biochemistry data to support project milestones and decision‑making
  • Collaborate with medicinal chemistry, structural biology, pharmacology, and other disciplines to advance compounds through discovery stages
  • Troubleshoot complex biochemical challenges and provide innovative solutions to overcome technical obstacles
  • Evaluate and implement emerging technologies and platforms to enhance biochemistry capabilities
Collaboration & Communication
  • Partner effectively with internal stakeholders across Research, Development, and Global functions
  • Build and maintain external collaborations with academic institutions, biotechnology companies, and contract research organizations
  • Present scientific findings and strategic recommendations to senior leadership
  • Contribute to scientific publications, patents, and presentations at external conferences
  • Participate in scientific advisory boards and industry forums as a Sanofi representative
Required Qualifications Education & Experience
  • Ph.D. in Biochemistry, Chemical Biology, Molecular Biology, or related scientific discipline and 8+ years of Progressive experience in pharmaceutical or biotechnology drug discovery industry
  • At least 5+ years of people management experience, including leading and developing scientific teams
  • Proven track record of contributions to successful drug discovery programs from early research through candidate selection
Technical Expertise
  • Deep expertise in biochemical assay development and characterization across multiple target classes (enzymes, protein‑protein interactions, epigenetic targets, etc.)
  • Strong understanding of enzyme kinetics, binding thermodynamics, and structure‑activity relationships
  • Hands‑on experience with diverse biochemical techniques including fluorescence, luminescence, mass spectrometry, surface plasmon resonance, and other biophysical methods
  • Knowledge of assay automation, high‑throughput screening, and data analysis methodologies
  • Expertise in the field of protein degradation or molecular glues (degraders‑non degraders)
  • Understanding of drug discovery processes from target identification through clinical candidate nomination
Leadership & Interpersonal Skills
  • Demonstrated ability to lead, motivate, and develop high‑performing scientific teams
  • Excellent strategic thinking and problem‑solving capabilities
  • Strong communication skills with ability to influence and align diverse stakeholders
  • Proven ability to manage multiple priorities and deliver results in a fast‑paced environment
  • Collaborative mindset with experience working in matrix organizations
Preferred Qualifications
  • Experience with novel therapeutic modalities such as targeted protein degradation, molecular glues, covalent inhibitors, or allosteric modulators
  • Expertise…
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