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Distinguished Scientist, Group Head Biochemistry
Job in
Somerville, Middlesex County, Massachusetts, 02145, USA
Listed on 2026-06-29
Listing for:
Sanofi
Full Time
position Listed on 2026-06-29
Job specializations:
-
Research/Development
Research Scientist -
Healthcare
Job Description & How to Apply Below
Key Responsibilities
- Provide strategic direction and scientific oversight for biochemistry activities supporting multiple drug discovery programs across diverse therapeutic areas
- Serve as the primary biochemistry expert and thought leader, guiding project teams on assay design, target characterization, and mechanism of action studies
- Drive innovation in biochemical assay technologies and methodologies to enhance drug discovery capabilities
- Establish and maintain scientific standards and best practices for biochemistry within In Vitro Biology
- Represent biochemistry expertise in cross‑functional project teams and governance committees
- Use AI/ML and robotics to accelerate drug discovery cycle times
- Lead, mentor, and develop a team of biochemists, fostering a culture of scientific excellence and collaboration
- Recruit, retain, and develop top scientific talent to build a world‑class biochemistry organization
- Conduct performance management, including goal setting, feedback, and career development for direct reports
- Create an inclusive environment that encourages innovation, continuous learning, and professional growth
- Promote Sanofi's values of Aim Higher, Act for Patients, Be Bold, and Lead Together within the team
- Oversee the design, development, and execution of biochemical assays for target validation, hit identification, and lead optimization
- Ensure timely delivery of high‑quality biochemistry data to support project milestones and decision‑making
- Collaborate with medicinal chemistry, structural biology, pharmacology, and other disciplines to advance compounds through discovery stages
- Troubleshoot complex biochemical challenges and provide innovative solutions to overcome technical obstacles
- Evaluate and implement emerging technologies and platforms to enhance biochemistry capabilities
- Partner effectively with internal stakeholders across Research, Development, and Global functions
- Build and maintain external collaborations with academic institutions, biotechnology companies, and contract research organizations
- Present scientific findings and strategic recommendations to senior leadership
- Contribute to scientific publications, patents, and presentations at external conferences
- Participate in scientific advisory boards and industry forums as a Sanofi representative
- Ph.D. in Biochemistry, Chemical Biology, Molecular Biology, or related scientific discipline and 8+ years of Progressive experience in pharmaceutical or biotechnology drug discovery industry
- At least 5+ years of people management experience, including leading and developing scientific teams
- Proven track record of contributions to successful drug discovery programs from early research through candidate selection
- Deep expertise in biochemical assay development and characterization across multiple target classes (enzymes, protein‑protein interactions, epigenetic targets, etc.)
- Strong understanding of enzyme kinetics, binding thermodynamics, and structure‑activity relationships
- Hands‑on experience with diverse biochemical techniques including fluorescence, luminescence, mass spectrometry, surface plasmon resonance, and other biophysical methods
- Knowledge of assay automation, high‑throughput screening, and data analysis methodologies
- Expertise in the field of protein degradation or molecular glues (degraders‑non degraders)
- Understanding of drug discovery processes from target identification through clinical candidate nomination
- Demonstrated ability to lead, motivate, and develop high‑performing scientific teams
- Excellent strategic thinking and problem‑solving capabilities
- Strong communication skills with ability to influence and align diverse stakeholders
- Proven ability to manage multiple priorities and deliver results in a fast‑paced environment
- Collaborative mindset with experience working in matrix organizations
- Experience with novel therapeutic modalities such as targeted protein degradation, molecular glues, covalent inhibitors, or allosteric modulators
- Expertise…
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