Senior Associate Scientist - Drug Product Development

Job Title: Senior Associate Scientist Drug Product Development

• Location:
  
  Cambridge, MA

This position supports the development of oral solid dosage formulations for small molecule drug products. The successful candidate will contribute to the design, development, and optimization of preclinical formulations (conventional and enabling) and clinical solid oral dosage forms (tablet and capsule), from early-stage development through scale-up and technology transfer to GMP manufacturing. Working under the guidance of senior team members and in close collaboration with cross-functional CMC teams, the candidate will apply hands‑on laboratory skills and foundational scientific knowledge to help advance drug candidates into clinical development.

Join the engine of Sanofi’s mission — where deep immunoscience meets bold, AI-powered research. In R&D, you’ll drive breakthroughs that could turn the impossible into possible for millions.

We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.

• Support the design and development of oral solid dosage formulations (tablets, capsules, granules) for preclinical and clinical programs

• Execute formulation studies including excipient compatibility testing, prototype development, and formulation optimization under guidance

• Contribute to the development of conventional and enabling formulations (e.g., amorphous dispersions) to help address bioavailability challenges

• Support formulation and process development activities, including granulation (wet and dry), blending, compression/tableting, and encapsulation

• Assist in applying DoE methodologies to optimize formulation and process parameters, with guidance from senior scientists

• Collaborate within the CMC team as a contributing team member, supporting defined deliverables and milestones

• Work with Analytical, Biopharm, Quality, and Regulatory colleagues to support alignment on development strategies

• Support Research team interactions to help evaluate molecular attributes relevant to drug delivery and formulation design

• Author and review technical reports, batch records, and supporting documentation with guidance from senior staff

• Ensure all documentation is accurate, complete, and compliant with requirements

• Maintain awareness of current scientific literature relevant to assigned projects

• Makes decisions that may require extrapolation of technical knowledge. Decisions generally impact own work and may impact the work group or project team.

• Independently plans standard and moderately complex experiments with relevant controls, with limited guidance from supervisor or subject matter experts. Able to plan and manage a set of concurrent experiments.

• Individual contributor. Understands the responsibilities of being a team member and adheres to appropriate documentation and safety practices.

• Presents internally within the functional group and to other local functions. May present to project or cross-functional teams as appropriate.

• Organizes own daily work to meet deadlines. Contributes to team objectives and short-term operational goals under supervision.

• Bachelor's degree OR Master's degree in Pharmaceutical Sciences, Chemistry, Chemical Engineering, Biomedical Engineering, Materials Science, Food Science, or a related life science/scientific/engineering discipline

• 4+ years (Bachelor's holders) OR 2+ years (Master's holders) of hands‑on experience in product or process development in a pharmaceutical, laboratory or related environment

• Experience with oral solid dosage formulation (tablets and/or capsules)

• Experience running dissolution studies using standard apparatus (USP2, USP4, USP7) and/or Pion equipment

• Solubility testing experience

• Academic or research experience will be considered but industry experience is required