Cellarity | Somerville, MA Scientist II​/Senior Scientist, Computational Biology

Scientist II / Senior Scientist, Computational Biology

Somerville, MA USA

What if you could join a rapidly growing company and play a critical role in bringing new medicines to patients through looking at and treating disease in a revolutionary way.

What this position is all about
:

Are you a highly motivated and detail-oriented computational biologist passionate about understanding complex biological systems and disease through single-cell omics and large-scale patient datasets
? This role offers a unique opportunity to contribute to the development and application of Cellarity’s platform. Specifically, you will identify disease-associated states from cell atlases and use our single-cell AI models to predict chemical entities that revert these states to healthy.

You will be part of a dynamic and innovative computational team focused on generating high-impact insights. Collaborating closely with world-class computational biologists, machine learning scientists, experimental biologists, chemists, clinicians
, and technologists
, you’ll help co-develop hypotheses, build proprietary data assets, and advance exploratory drug programs.

If you’re excited about applying your skills to real-world therapeutic challenges, working with proprietary, high-quality datasets, and learning from leading experts across disciplines, we want to hear from you.

What you would be responsible for:

• Apply computational biology and machine learning tools to generate insights and hypotheses from high-dimensional molecular datasets, with a focus on large-scale scRNA-seq & snRNA-seq disease atlases.
• Develop & lead data analysis strategies and ideation across diverse biological and clinically relevant projects with internal and external stakeholders.
• Act as the computational biology co-lead on drug programs, working with experimental scientists to ensure that study designs & data are properly interrogated to deliver high value readouts.
• Present your results in an interdisciplinary team of biologists, chemists, clinicians, technologists, and other machine learning colleagues in meetings covering cross-functional project teams, functional teams, to whole company and management meetings.

What experiences will you need:

• Ph.D. or equivalent in biology, computational biology, or related scientific field.
• 2+ years of relevant experience post Ph.D.
• Extensive experience in analyzing and deriving hypothesis from single-cell transcriptomic data, preferably also with large-scale single-cell atlases.
• Demonstrated scientific understanding of molecular and systems biology, diverse molecular data types, and analysis tools.
• Practical programming and scripting skills, preferably in Python.
• Fast learner, analytical thinker, creative, "hands-on", strong communication skills.
• Able to work both independently and as part of a team.

What sets you apart:

• Background in metabolic or liver diseases, autoimmune disease, or hematology.
• Experience with generating, analyzing, and deriving hypotheses from other single-cell omics data types or large-scale clinical datasets.
• Experience driving an impactful and relevant project within industry.
• Background in statistics or machine learning.
• Experience with clinical or biological data.
• Interested in learning any of the above.

At Cellarity, we

• Push Boundaries: We create a legacy with breakthrough science in service of patients.
• Inject Energy: We build strengths from different perspectives and tell it like it is
• Own it: We transcend our job descriptions and relentlessly follow through on our commitments.
• Go all out: We work quickly and with conviction.

Company

Summary:

Cellarity’s mission is to fundamentally redesign the way drugs are created for the sake of bringing new hope to patients. By shifting the…