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Director, Commercial Accounting

Job in South San Francisco, San Mateo County, California, 94083, USA
Listing for: Initial Therapeutics, Inc.
Full Time position
Listed on 2026-08-22
Job specializations:
  • Finance & Banking
    Financial Reporting, Chief Financial Officer (CFO), VP/Director of Finance, Financial Analyst
Salary/Wage Range or Industry Benchmark: 198000 - 245000 USD Yearly USD 198000.00 245000.00 YEAR
Job Description & How to Apply Below

Job Summary

About IDEAYA Biosciences: IDEAYA is a precision medicine oncology company committed to the discovery, development, and commercialization of transformative therapies for cancer. Our approach integrates expertise in small-molecule drug discovery, structural biology and bioinformatics with robust internal capabilities in identifying and validating translational biomarkers to develop tailored, potentially first-in-class targeted therapies aligned to the genetic drivers of disease. We have built a deep pipeline of product candidates focused on synthetic lethality and antibody-drug conjugates, or ADCs, for molecularly defined solid tumor indications.

Our mission is to bring forth the next wave of precision oncology therapies that are more selective, more effective, and deeply personalized with the goal of altering the course of disease and improving clinical outcomes for patients with cancer.

When you're at IDEAYA, you will be in the midst of brilliant minds working on precision medicine therapies to help cancer patients. We are passionate and committed about being on the forefront of oncology medicine, which means we all have a high internal drive that is at the very core of every person  are inquisitive, ask deep questions, and are data-driven innovators who like to collaborate and use teamwork to move science forward.

For more information, please see

Location:

South San Francisco, CA

Position Summary

IDEAYA Biosciences is seeking a Director, Commercial Accounting. The Director, Commercial Accounting is a strategic finance leader responsible for overseeing all aspects of commercial product revenue accounting, gross-to-net (GTN) reporting and forecasting. Reporting to the Chief Accounting Officer, this role will ensure accurate revenue recognition in accordance with U.S. GAAP while building scalable processes, systems, and controls to support IDEAYA’s transition to and growth as a commercial-stage biotechnology company.

This leader will serve as the subject matter expert for gross-to-net methodologies, revenue analytics, including building forecast models, and partnering cross-functionally with Commercial, Market Access, Government Pricing, Supply Chain, Manufacturing, FP&A, and Compliance teams to ensure financial integrity, margin visibility, and forecast accuracy. This position is based in our South San Francisco headquarter offices and is required to be onsite four days per week per our company policy.

Reporting to:
Senior Director, Finance

Job Description

What you’ll do:

  • Lead all aspects of commercial product revenue accounting, including gross-to-net estimates, accruals, and revenue recognition in compliance with ASC 606.
  • Oversee development, validation, and continuous improvement of gross-to-net forecasting methodologies, including rebates, chargebacks, returns, distribution fees, patient assistance programs, and other variable consideration components.
  • Partner with Commercial, Market Access, Trade, and Government Pricing to align GTN assumptions with contracting strategies and payer dynamics.
  • Oversee monthly, quarterly, and annual revenue close processes, including variance analysis and executive reporting.
  • Establish and maintain robust internal controls over revenue processes, ensuring SOX compliance and audit readiness.
  • Drive visibility into gross margin performance, including detailed analysis of cost drivers and scenario modeling for launch and scale-up activities.
  • Collaborate with FP&A to integrate GTN and COGS analytics into budgeting, long-range planning, and scenario modeling.
  • Support implementation and optimization of ERP systems and revenue/cost accounting modules to enable scalable commercial operations.
  • Serve as a key liaison with external auditors regarding revenue recognition and related GTN methodologies.

Requirements:

  • Bachelor’s degree in Accounting or Finance; CPA strongly preferred.
  • 12+ years of progressive accounting and finance experience, including 5+ years in a leadership role within a commercial-stage life sciences or biotechnology company.
  • Deep expertise in U.S. GAAP revenue recognition (ASC 606), and gross-to-net accounting in the pharmaceutical/biotech industry.…
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