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Vice President and U.S. Squad Leader, Neurodegeneration; ND

Job in South San Francisco, San Mateo County, California, 94083, USA
Listing for: Genentech
Full Time position
Listed on 2026-03-01
Job specializations:
  • Healthcare
    Healthcare Management
Salary/Wage Range or Industry Benchmark: 100000 - 125000 USD Yearly USD 100000.00 125000.00 YEAR
Job Description & How to Apply Below
Position: Vice President and U.S. Squad Leader, Neurodegeneration (ND)

The Position

Vice President and U.S. Squad Leader, Neurodegeneration (ND)

Commercial Portfolio Organization (CPO) | Genentech

Alzheimer's and Parkinson's diseases have stolen memories, mobility, and lives for decades. We are finally armed with the science to fight back.

We are building a robust neurodegeneration pipeline. It includes our flagship Alzheimer's therapy, trontinemab, and key Parkinson's assets like prasinezumab. In addition, our Diagnostics colleagues have developed and are poised to commercialize ground-breaking blood based biomarkers for Alzheimer’s which will allow us to radically re‑shape patient journeys and care models. But a pipeline does not save lives on its own. We need a commercial engine to put these medicines into the hands of patients.

We are seeking a Vice President and U.S. Squad Leader for Neurodegeneration. You will build this engine.

The Role

You hold single-point accountability for the P&L, strategy, and successful commercialization of our entire U.S. neurodegeneration portfolio. You will report directly to the Senior Vice President of the Commercial Portfolio Organization (CPO) and sit on the CPO Leadership Team (CPOLT).

You are not just launching drugs. You are building a new market. Treating neurodegeneration requires systemic changes in healthcare delivery. You will design the strategy and assemble the exact cross‑functional Squad—including Medical, Marketing, Access, Field, and Operations—needed to execute it. You will also design and execute a novel commercialization model with our Roche Diagnostics colleagues to drive radical shifts in the way Alzheimer’s is identified and treated.

Key Accountabilities

  • Build the ND Squad and Network:
    You will recruit, motivate, and lead a cross‑functional network. You will define the required capabilities to win, from Key Account Managers targeting top‑tier neurology clinics to specialized field teams focused on diagnostic pathways.
  • Commercialize the Pipeline:
    You will lead the U.S. go‑to‑market strategy for our pipeline assets. Your immediate focus will be preparing the market for our Phase 1b/2a trontinemab readout and advancing our Parkinson's strategy.
  • Shape the Healthcare Ecosystem:
    You will clear the bottlenecks that keep patients from care. You will direct strategies to build clinical infrastructure, establish precise diagnostic pathways (PET scans, blood biomarkers, and CSF tests), and expand site‑of‑care capacity.
  • Enterprise Stewardship:
    You will represent the U.S. perspective in global R&D and pipeline investment decisions. You will partner seamlessly with Global Product Strategy (GPS), Product Development (PD), and Pharma Technical (PT) to ensure our medicines reach the U.S. market quickly and safely.
  • External Leadership:
    You will act as Genentech’s primary spokesperson for neurodegeneration. You will build deep, trusted relationships with patient advocates, therapeutic area experts, payers, and policymakers.

What You Will Deliver

  • Business Impact:
    You will secure resources, build the commercial infrastructure, and consistently meet ambitious financial and launch readiness targets.
  • Patient Impact:
    You will measure your success by lives changed. More patients diagnosed accurately. More patients starting our treatments, faster. More families are given hope.
  • Cultural Leadership:
    You will foster a culture of speed, precision, and psychological safety. You will manage your Squad like direct reports, coaching top talent and insisting on learning over perfection.

Our Operating Principles

  • Put Patients First: I always act as if patients I know are in the room and do what’s best for them.
  • Follow the science: I seek answers through experiments, data and debate, and act on facts.
  • Act as one team: I care, collaborate and commit without boundaries, and trust others to do their part.
  • Embrace differences: I seek diverse perspectives, invite opposing views, and challenge myself and others.
  • Accelerate learning: I push to learn new things even if difficult, and openly share my successes and failures.
  • Simplify radically: I eliminate complexity, reuse with pride, and accomplish more with less.
  • Make impact now: I take accountability to do what is right,…
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